Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 known ✓ | P35354 | 8/20 | 0.52 |
| ▸ | CA12 known ✓ | O43570 | 2/20 | 0.42 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.42 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.42 |
| ▸ | PTGS1 known ✓ | P23219 | 3/20 | 0.40 |
| ▸ | PKLR | P30613 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | PGAM1 | P18669 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | HGF | P14210 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL310987 | 1.00 | PTGS2 (0.52) | PTGS2PKLRCA12CA1CA2 | |
| SCHEMBL28227505 | 1.00 | PTGS2 (0.52) | PTGS2PKLRCA12CA1CA2 | |
| Water SCHEMBL15672825 | 0.98 | PTGS2 (0.50) | PTGS2PKLRCA12CA1CA2 | |
| Water SCHEMBL31291030 | 0.98 | PTGS2 (0.50) | PTGS2PKLRCA12CA1CA2 | |
| Potassium Ion SCHEMBL14740336 | 0.96 | PTGS2 (0.52) | PTGS2PKLRCA12CA1CA2 | |
| SCHEMBL1870051 | 0.94 | PTGS2 (0.48) | PTGS2PKLRCA12CA1CA2 | |
| SCHEMBL29194064 | 0.94 | PTGS2 (0.48) | PTGS2PKLRCA12CA1CA2 | |
| SCHEMBL31276980 | 0.94 | PTGS2 (0.48) | PTGS2PKLRCA12CA1CA2 | |
| SCHEMBL28177146 | 0.91 | PTGS2 (0.44) | PTGS2PKLRCA12CA1CA2 | |
| Lithium Ion SCHEMBL3173871 | 0.89 | PTGS2 (0.48) | PTGS2PKLRCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3381448-B1 | ORAL HEMOSTATIC AND WOUND-PROTECTIVE FILM | TBM COMPANY (KR) | 2025-01-01 | — | — | EP | disclosed |