Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 10/20 | 0.55 |
| ▸ | THRA | P10827 | 7/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GRN | P28799 | 1/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16740573 | 0.91 | THRA (0.47) | THRBTHRACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8161806 | 0.91 | THRA (0.47) | THRBTHRACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL16740674 | 0.91 | TGM2 (0.47) | THRBTHRACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11092024 | 0.90 | CYP3A4 (0.58) | THRBTHRACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9422511 | 0.89 | THRB (0.54) | THRBTHRACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL16740537 | 0.88 | ALDH1A1 (0.47) | THRBTHRACYP3A4ALDH1A1MEN1 | |
| SCHEMBL16740667 | 0.85 | TGM2 (0.45) | THRBTHRACYP2C19ALDH1A1TGM2 | |
| SCHEMBL17544219 | 0.81 | PPARA (0.51) | CYP3A4ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL15416126 | 0.80 | CYP2C19 (0.44) | THRBTHRACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL16740570 | 0.74 | AKR1B1 (0.43) | THRBTHRACYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166274-B2 | Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds | L'OREAL (FR) | 2007-01-23 | — | — | US | claimed |
| US-20040047820-A1 | Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds | SOCIETE L'OREAL S.A. (FR) | 2004-03-11 | — | — | US | claimed |
| US-6627180-B2 | Particles having protection factor UV-APPD and an amino substituted 2-hydroxybenzophenone | SOCIETE L'OREAL S.A. (FR) | 2003-09-30 | — | — | US | claimed |
| US-20030152532-A1 | SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS | SOCIETE L'OREAL S.A. (FR) | 2003-08-14 | — | — | US | claimed |
| EP-1317918-A1 | Cosmetic sunscreen compositions based on synergistic filter mixture and their use | L'OREAL (FR) | 2003-06-11 | — | — | EP | claimed |
| EP-3709966-B1 | COMPOSITIONS COMPRISING AT LEAST ONE ACRYLIC POLYMER AND AT LEAST ONE INSOLUBLE ORGANIC SCREENING AGENT | OREAL (FR) | 2024-12-11 | — | — | EP | disclosed |
| US-20210346249-A1 | COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER | L'OREAL (FR) | 2021-11-11 | — | — | US | disclosed |
| CN-107847414-B | Composition comprising a UV screening agent, an anionically crosslinked hydrophilic polymer, a surfactant having an HLB less than or equal to 5, and a siloxane copolymer | 欧莱雅 | 2021-09-10 | — | — | CN | disclosed |
| EP-3185843-B1 | GEL COMPOSITION AND GEL COMPRISING A UV FILTER | OREAL (FR) | 2021-08-11 | — | — | EP | disclosed |
| EP-2872107-B1 | COSMETIC COMPOSITION CONTAINING SCREENING COMPOSITE PARTICLES | OREAL (FR) | 2021-07-21 | — | — | EP | disclosed |
| US-20200360264-A1 | COMPOSITIONS COMPRISING AT LEAST ONE ACRYLIC POLYMER AND AT LEAST ONE INSOLUBLE ORGANIC SCREENING AGENT | L'OREAL (FR) | 2020-11-19 | — | — | US | disclosed |
| CN-111343968-A | Composition comprising at least one acrylic polymer and at least one insoluble organic masking agent | 莱雅公司 | 2020-06-26 | — | — | CN | disclosed |
| US-20040047820-A1 | Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds | SOCIETE L'OREAL S.A. (FR) | 2004-03-11 | — | — | US | disclosed |
| US-6627180-B2 | Particles having protection factor UV-APPD and an amino substituted 2-hydroxybenzophenone | SOCIETE L'OREAL S.A. (FR) | 2003-09-30 | — | — | US | disclosed |
| US-20030152532-A1 | SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS | SOCIETE L'OREAL S.A. (FR) | 2003-08-14 | — | — | US | disclosed |
| US-20030129151-A1 | Use of amphiphilic copolymers to stabilize dispersions of insoluble organic compounds for screening out UVradiation, dispersions stabilized with these copolymers and cosmetic compositions containing them | L'OREAL (FR) | 2003-07-10 | — | — | US | disclosed |
| EP-1317918-A1 | Cosmetic sunscreen compositions based on synergistic filter mixture and their use | L'OREAL (FR) | 2003-06-11 | — | — | EP | disclosed |
| EP-1302197-A1 | Use of amphiphilic copolymers to stabilise dispersions of non-soluble organic compounds filtering UV light | L'OREAL (FR) | 2003-04-16 | — | — | EP | disclosed |
| US-20030053966-A1 | Insoluble organic UV screening agents of aryl vinylene ketone type, and cosmetic use thereof | L'OREAL (FR) | 2003-03-20 | — | — | US | disclosed |
| EP-1281391-A1 | Organic insoluble UV filters of the aryl vinylene ketone type and their use in cosmetics | L'OREAL (FR) | 2003-02-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030129151-A1 | Use of amphiphilic copolymers to stabilize dispersions of insoluble organic compounds for screening out UVradiation, dispersions stabilized with these copolymers and cosmetic compositions containing them | CUTA, HNRNPU, ERCC5 | THRB 4747/4885THRA 4568/4885CYP3A4 2458/4885 |
| US-20200360264-A1 | COMPOSITIONS COMPRISING AT LEAST ONE ACRYLIC POLYMER AND AT LEAST ONE INSOLUBLE ORGANIC SCREENING AGENT | PCNA, ERCC1, XRCC6 | THRB 4670/4885THRA 3101/4885CYP3A4 4560/4885 |
| US-20040047820-A1 | Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds | SUCLG1, CUTA, DLD | THRB 4774/4885THRA 4808/4885CYP3A4 1252/4885 |
| US-20030053966-A1 | Insoluble organic UV screening agents of aryl vinylene ketone type, and cosmetic use thereof | PRKDC, AHR, TYR | THRB 4007/4885THRA 2553/4885CYP3A4 535/4885 |
| US-20210346249-A1 | COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER | ERCC5, CUTA, PLIN5 | THRB 1865/4885THRA 2738/4885CYP3A4 3517/4885 |
| US-20030152532-A1 | SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS | HADHB, SDHA, ERCC4 | THRB 3677/4885THRA 4123/4885CYP3A4 700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.