SCHEMBL3152309

SCHEMBL3152309

Cc1ccnc2ncccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 3/20 0.52
CCR8 P51685 3/20 0.52
CCR5 P51681 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
PSMD14 O00487 2/20 0.48
COPS5 Q92905 2/20 0.48
SLC6A2 P23975 1/20 0.48
HTT P42858 1/20 0.48
NPC1 O15118 1/20 0.48
HSP90AA1 P07900 1/20 0.48
NOS3 P29474 3/20 0.43
NOS2 P35228 3/20 0.43
NOS1 P29475 1/20 0.43
KDM4E B2RXH2 1/20 0.42
MAPT P10636 1/20 0.42
CYP1A2 P05177 2/20 0.42
CYP2A6 P11509 2/20 0.42
LMNA P02545 1/20 0.41
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30718598 1.00 CCR1 (0.52) CCR1CCR8CCR5L3MBTL1PSMD14
Hydrochloric Acid SCHEMBL3320735 0.98 CCR1 (0.50) CCR1CCR8CCR5L3MBTL1PSMD14
SCHEMBL3143662 0.76 CCR1 (0.54) CCR1CCR8CCR5L3MBTL1PSMD14
SCHEMBL10781627 0.74 CCR1 (0.67) CCR1CCR8CCR5L3MBTL1PSMD14
SCHEMBL18624181 0.74 L3MBTL1 (0.42) CCR1CCR8CCR5L3MBTL1PSMD14
SCHEMBL14227400 0.74 CYP1A2 (0.52) CCR1CCR8CCR5L3MBTL1PSMD14
SCHEMBL12341491 0.73 CCR1 (0.46) CCR1CCR8CCR5L3MBTL1PSMD14
SCHEMBL10714074 0.73 CCR1 (0.52) CCR1CCR8CCR5L3MBTL1PSMD14
SCHEMBL31662896 0.73 L3MBTL1 (0.45) CCR1CCR8L3MBTL1PSMD14COPS5
SCHEMBL12560150 0.73 L3MBTL1 (0.45) CCR1CCR8L3MBTL1PSMD14COPS5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 214 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240067632-A1 WEE1 Degrading Compounds and Uses Thereof BRISTOL-MYERS SQUIBB COMPANY (US) 2024-02-29 US disclosed
US-20240018175-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS AND ELECTRONIC EQUIPMENT INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2024-01-18 US disclosed
US-11825740-B2 Amine compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-21 US disclosed
US-20230250096-A1 SUBSTITUTED PHENYL-1H-PYRROLO[2,3-c] PYRIDINE DERIVATIVES JANSSEN PHARMACEUTICA NV (BE) 2023-08-10 US disclosed
US-20230250096-A1 SUBSTITUTED PHENYL-1H-PYRROLO[2,3-c] PYRIDINE DERIVATIVES JANSSEN PHARMACEUTICA NV (BE) 2023-08-10 US disclosed
US-11696499-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-04 US disclosed
US-11690289-B2 Organic compound containing heterocyclic ring and having low lumo properties, and organic electroluminescent device using the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-27 US disclosed
WO-2023110138-A1 INHIBITORS OF TRANSGLUTAMINASES ZEDIRA GMBH (DE) 2023-06-22 WO disclosed
US-20230183239-A1 ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE 1 (ENPP-1) INHIBITORS AND USES THEREOF ABBVIE INC (US) 2023-06-15 US disclosed
US-11678498-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-13 US disclosed
WO-2006063039-A2 3, 6-BICYCLOLIDES ENANTA PHARMACEUTICALS, INC. (US) 2006-06-15 WO disclosed
EP-0161164-B1 PROCESS FOR PREPARING POLYPHENYLENETHERS Montedison S.p.A. (IT) 1988-06-22 EP disclosed
US-4639506-A OXIDATIVE POLYMERIZATION OF A PHENOL MONTEDISON S.P.A. (IT) 1987-01-27 US disclosed
EP-0161164-A1 Process for preparing polyphenylenethers Montedison S.p.A. (IT) 1985-11-13 EP disclosed
US-4273862-A ANIONIC CYANINE DYE, HYDROQUINONE FRBRLOPRT MITSUBISHI PAPER MILLS, LTD. (JP) 1981-06-16 US disclosed
US-4259439-A DIMETHINECYANINE DYE SENSITIZER MITSUBISHI PAPER MILLS, LTD. (JP) 1981-03-31 US disclosed
US-4175965-A SILVER HALIDE EMULSION CONTAINING AN ELECTRON ACCEPTOR AND A SENSITIZING DYE MITSUBISHI PAPER MILLS, LTD. (JP) 1979-11-27 US disclosed
US-4147554-A 5,6-DIHYDRO-PYRROLO(2,1-A)ISOQUINOLINES MITSUBISHI PAPER MILLS, LTD. (JP) 1979-04-03 US disclosed
US-4134769-A BETAINE AND ANIONIC TYPE CYANINE DYES MITSUBISHI PAPER MILLS, LTD. (JP) 1979-01-16 US disclosed
US-3966931-A TRANQUILIZERS, ANTICONVULSANTS, HYPNOSIS RHONE-POULENC S.A. (FR) 1976-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240018175-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS AND ELECTRONIC EQUIPMENT INCLUDING THE LIGHT-EMITTING DEVICE GPX1, LAGE3, NFE2L2 CCR1 3530/4885CCR8 4050/4885CCR5 3999/4885
US-11690289-B2 Organic compound containing heterocyclic ring and having low lumo properties, and organic electroluminescent device using the same LEF1, PPOX, LIMK1 CCR1 2802/4885CCR8 4000/4885CCR5 3235/4885
US-20230250096-A1 SUBSTITUTED PHENYL-1H-PYRROLO[2,3-c] PYRIDINE DERIVATIVES MLLT1, BMI1, MEN1 CCR1 2308/4885CCR8 4026/4885CCR5 3197/4885
US-20230183239-A1 ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE 1 (ENPP-1) INHIBITORS AND USES THEREOF ENPP1, ENPP3, STING1 CCR1 2165/4885CCR8 2667/4885CCR5 1440/4885
US-20240067632-A1 WEE1 Degrading Compounds and Uses Thereof WEE1, WEE2, PPME1 CCR1 4181/4885CCR8 3985/4885CCR5 4526/4885
US-11825740-B2 Amine compound and organic light-emitting device including the same AOC2, AOC1, AOC3 CCR1 2856/4885CCR8 3785/4885CCR5 3319/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.