Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9514799 | 0.81 | DHFR (0.33) | — | |
| SCHEMBL11794334 | 0.78 | ESR1 (0.31) | ESR1S1PR1 | |
| SCHEMBL252675 | 0.75 | CHKA (0.43) | CHKA | |
| SCHEMBL900235 | 0.75 | TSHR (0.38) | ESR1 | |
| SCHEMBL7016068 | 0.75 | TSHR (0.35) | ESR1 | |
| SCHEMBL11032897 | 0.74 | CHKA (0.46) | CHKAESR1S1PR1 | |
| SCHEMBL83762 | 0.74 | CHKA (0.46) | CHKAESR1S1PR1 | |
| SCHEMBL821817 | 0.74 | CHKA (0.42) | CHKA | |
| SCHEMBL130243 | 0.74 | ALDH1A1 (0.44) | — | |
| SCHEMBL3435320 | 0.73 | CHKA (0.36) | CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8350014-B2 | Preparation of diazo and diazonium compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-01-08 | — | — | US | claimed |
| WO-2010057220-A1 | PREPARATION OF DIAZO AND DIAZONIUM COMPOUNDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-05-20 | — | — | WO | claimed |
| US-20100125132-A1 | PREPARATION OF DIAZO AND DIAZONIUM COMPOUNDS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2010-05-20 | — | — | US | claimed |
| US-5069999-A | PRESENSITIZED | FUJI PHOTO FILM CO., LTD. (JP) | 1991-12-03 | — | — | US | claimed |
| US-8871916-B2 | Diaryl phosphine compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-10-28 | — | — | US | disclosed |
| US-20130203974-A1 | Preparation of Diazo and Diazonium Compounds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-08-08 | — | — | US | disclosed |
| US-8436031-B2 | Transcription factor modulating compounds and methods of use thereof | PARATEK PHARMACEUTICALS, INC. (US) | 2013-05-07 | — | — | US | disclosed |
| US-8350014-B2 | Preparation of diazo and diazonium compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-01-08 | — | — | US | disclosed |
| US-20110306611-A1 | Transcription factor modulating compounds and methods of use thereof | PARATEK PHARMACEUTICALS, INC. (US) | 2011-12-15 | — | — | US | disclosed |
| US-20100168108-A1 | PHENYL DERIVATIVES AND METHODS OF USE | ADOLOR CORPORATION (US) | 2010-07-01 | — | — | US | disclosed |
| WO-2010057220-A1 | PREPARATION OF DIAZO AND DIAZONIUM COMPOUNDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-05-20 | — | — | WO | disclosed |
| US-20100125132-A1 | PREPARATION OF DIAZO AND DIAZONIUM COMPOUNDS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2010-05-20 | — | — | US | disclosed |
| EP-0622665-A1 | Silver halide photographic light-sensitive material | KONICA CORPORATION (JP) | 1994-11-02 | — | — | EP | disclosed |
| US-4874391-A | USING WATER SOLUBLE COPPER COMPLEX AZO DYE, LIGHT STABILIZER AND ANTIOXIDANT | CIBA-GEIGY CORPORATION (US) | 1989-10-17 | — | — | US | disclosed |
| US-4780399-A | SENSITIZING-DYE HAVING OXAZOLE, THIAZOLE, IMIDAZOLE RINGS OR BENZO-AND NAPHTHO-COMPLETING DERIVATIVES | FUJI PHOTO FILM CO., LTD. (JP) | 1988-10-25 | — | — | US | disclosed |
| EP-0105425-B1 | SILVER HALIDE PHOTOGRAPHIC LIGHT SENSITIVE MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1987-05-27 | — | — | EP | disclosed |
| US-4609621-A | REDUCED DEPENDENCE ON DEVELOPMENT PROCESSING CONDITIONS | FUJI PHOTO FILM CO., LTD. (JP) | 1986-09-02 | — | — | US | disclosed |
| EP-0105425-A2 | Silver halide photographic light sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1984-04-18 | — | — | EP | disclosed |
| US-4047964-A | BENZISOXAZOLE | FUJI PHOTO FILM CO., LTD. (JA) | 1977-09-13 | — | — | US | disclosed |
| US-4040841-A | SENSITIZING DYE | FUJI PHOTO FILM CO., LTD. (JA) | 1977-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110306611-A1 | Transcription factor modulating compounds and methods of use thereof | JUN, CREBBP, TFEB | CHKA 4101/4885ESR1 1735/4885S1PR1 4705/4885 |
| US-20100125132-A1 | PREPARATION OF DIAZO AND DIAZONIUM COMPOUNDS | TREH, TALDO1, LIPE | CHKA 2147/4885ESR1 3802/4885S1PR1 2720/4885 |
| US-20130203974-A1 | Preparation of Diazo and Diazonium Compounds | TREH, TALDO1, LIPE | CHKA 2147/4885ESR1 3802/4885S1PR1 2720/4885 |
| US-20100168108-A1 | PHENYL DERIVATIVES AND METHODS OF USE | CNR2, CNR1, GPR119 | CHKA 607/4885ESR1 1653/4885S1PR1 383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.