Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2589475 | 0.85 | TSHR (0.41) | ALDH1A1HSD17B10KMT2AKDM4ELMNA | |
| SCHEMBL6256662 | 0.79 | CES2 (0.41) | CES2CES1ALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL14053556 | 0.78 | ALDH1A1 (0.40) | CES2CES1ALDH1A1HSD17B10KMT2A | |
| SCHEMBL1116304 | 0.78 | CYP3A4 (0.36) | ALDH1A1HSD17B10POLBKDM4ETSHR | |
| SCHEMBL1116324 | 0.78 | KDM4E (0.43) | ALDH1A1HSD17B10POLBKDM4ELMNA | |
| SCHEMBL3264512 | 0.78 | ALDH1A1 (0.40) | CES2CES1ALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL653173 | 0.77 | FSCN1 (0.51) | ALDH1A1HSD17B10KDM4ETSHR | |
| SCHEMBL2588967 | 0.77 | ALDH1A1 (0.41) | ALDH1A1HSD17B10KMT2APOLBKDM4E | |
| SCHEMBL7995828 | 0.76 | CES2 (0.39) | CES2CES1ALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL4919799 | 0.76 | SIGMAR1 (0.42) | ALDH1A1KMT2APOLBKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10711026-B2 | Spinosyn derivatives as insecticides | AGRIMETIS, LLC (US) | 2020-07-14 | — | — | US | disclosed |
| EP-3344610-B1 | SPINOSYN DERIVATIVES AS INSECTICIDES | AGRIMETIS LLC (US) | 2020-05-06 | — | — | EP | disclosed |
| US-20190309007-A1 | SPINOSYN DERIVATIVES AS INSECTICIDES | CORTEVA AGRISCIENCE LLC | 2019-10-10 | — | — | US | disclosed |
| EP-3344610-A1 | SPINOSYN DERIVATIVES AS INSECTICIDES | Agrimetis, LLC (US) | 2018-07-11 | — | — | EP | disclosed |
| WO-2017040882-A1 | SPINOSYN DERIVATIVES AS INSECTICIDES | AGRIMETIS, LLC (US) | 2017-03-09 | — | — | WO | disclosed |
| US-8426437-B2 | Pyrroloquinoline derivatives and their use as protein kinases inhibitors | PIERRE FABRE MEDICAMENT (FR) | 2013-04-23 | — | — | US | disclosed |
| WO-2012162468-A1 | THIAZOL DERIVATIVES AS PRO -MATRIX METALLOPROTEINASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2012-11-29 | — | — | WO | disclosed |
| US-20120302573-A1 | METHODS OF INHIBITING PRO MATRIX METALLOPROTEINASE ACTIVATION | JANSSEN PHARMACEUTICA NV (BE) | 2012-11-29 | — | — | US | disclosed |
| EP-1899335-B1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PF MEDICAMENT (FR) | 2010-05-19 | — | — | EP | disclosed |
| US-20090042876-A1 | Pyrroloquinoline Derivatives And Their Use As Protein Kinases Inhibitors | PIERRE FABRE MEDICAMENT (FR) | 2009-02-12 | — | — | US | disclosed |
| EP-1899335-A1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PIERRE FABRE MEDICAMENT (FR) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007003611-A1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PIERRE FABRE MEDICAMENT (FR) | 2007-01-11 | — | — | WO | disclosed |
| US-4816235-A | Silver and manganese recovery using acidified thiourea | PESIC BATRIC (US) | 1989-03-28 | — | — | US | disclosed |
| US-4778519-A | Recovery of precious metals from a thiourea leach | PESIC BATRIC (US) | 1988-10-18 | — | — | US | disclosed |
| US-3994719-A | Resins for separating heavy metals consisting of thiourea-group-containing macroporous vinyl aromatic crosslinked matrixes | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120302573-A1 | METHODS OF INHIBITING PRO MATRIX METALLOPROTEINASE ACTIVATION | MMP13, MMP8, MMP11 | CES2 1091/4885CES1 593/4885ALDH1A1 1395/4885 |
| US-20190309007-A1 | SPINOSYN DERIVATIVES AS INSECTICIDES | SPIN3, ACHE, SPIN4 | CES2 670/4885CES1 243/4885ALDH1A1 3794/4885 |
| US-10711026-B2 | Spinosyn derivatives as insecticides | SPIN3, ACHE, SPIN4 | CES2 670/4885CES1 243/4885ALDH1A1 3794/4885 |
| US-20090042876-A1 | Pyrroloquinoline Derivatives And Their Use As Protein Kinases Inhibitors | MAP3K1, MAP3K2, MAP3K7 | CES2 3846/4885CES1 3628/4885ALDH1A1 3830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.