Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | ADH1B | P00325 | 1/20 | 0.43 |
| ▸ | ADH1C | P00326 | 1/20 | 0.43 |
| ▸ | ADH1A | P07327 | 1/20 | 0.43 |
| ▸ | ADH7 | P40394 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 3/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8374192 | 0.79 | MAOB (0.50) | MAOBCTSLCTSBCYP2C19IDO1 | |
| SCHEMBL8374191 | 0.79 | MAOB (0.50) | MAOBCTSLCTSBCYP2C19IDO1 | |
| SCHEMBL8541497 | 0.79 | MAOB (0.50) | MAOBCTSLCTSBCYP2C19IDO1 | |
| SCHEMBL8374190 | 0.79 | MAOB (0.50) | MAOBCTSLCTSBCYP2C19IDO1 | |
| Phenylalanine SCHEMBL11571873 | 0.79 | SLC7A5 (0.69) | IDO1NOS3NOS1NOS2ALPI | |
| SCHEMBL21233204 | 0.78 | SIGMAR1 (0.48) | ADH1BADH1CADH1AADH7CYP2C19 | |
| SCHEMBL10780317 | 0.76 | ESR1 (0.44) | CYP2C19IDO1CA2 | |
| SCHEMBL22305170 | 0.76 | CYP1A2 (0.56) | CYP2C19POLBHSD17B10DAOALPL | |
| SCHEMBL9217995 | 0.75 | MAOB (0.46) | MAOBCTSLCTSBCYP2C19IDO1 | |
| SCHEMBL2534699 | 0.75 | MAOB (0.46) | MAOBCTSLCTSBCYP2C19IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194693-A1 | Aminoacetonitrile Derivatives and Their Use for Controlling Parasites on Warm-Blooded Animals | NOVARTIS AG (CH) | 2008-08-14 | — | — | US | claimed |
| EP-1758849-A1 | AMINOACETONITRILE DERIVATIVES AND THEIR USE FOR CONTROLLING PARASITES ON WARM-BLOODED ANIMALS | Novartis AG (CH) | 2007-03-07 | — | — | EP | claimed |
| WO-2005121075-A1 | AMINOACETONITRILE DERIVATIVES AND THEIR USE FOR CONTROLLING PARASITES ON WARM-BLOODED ANIMALS | NOVARTIS AG (CH) | 2005-12-22 | — | — | WO | claimed |
| US-12258349-B2 | Anti-viral drug | DORING INTERNATIONAL GMBH (CH) | 2025-03-25 | — | — | US | disclosed |
| US-20230150968-A1 | SUBSTITUTED THIOPHENE CARBOXAMIDES AND DERIVATIVES THEREOF AS MICROBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-05-18 | — | — | US | disclosed |
| US-20230132621-A1 | 1,5-DIHYDRO-2,4-BENZODIAZEPINE-3-ONE DERIVATIVE AND APPLICATION THEREOF | JIANGSU NHWA PHARMACEUTICAL CO., LTD (CN) | 2023-05-04 | — | — | US | disclosed |
| US-20230055705-A1 | SUBSTITUTED THIOPHENE CARBOXAMIDES AND DERIVATIVES THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2023-02-23 | — | — | US | disclosed |
| US-20230046892-A1 | SUBSTITUTED THIOPHENE CARBOXAMIDES, THIOPHENE CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2023-02-16 | — | — | US | disclosed |
| US-20220298164-A1 | ANTI-VIRAL DRUG | DORING INTERNATIONAL GMBH (CN) | 2022-09-22 | — | — | US | disclosed |
| US-11370797-B2 | Anti-viral drug | DORING INTERNATIONAL GMBH (CH) | 2022-06-28 | — | — | US | disclosed |
| CN-109053548-A | A kind of carbazolyl-containing Schiff and preparation method thereof | 陕西科技大学 | 2018-12-21 | — | — | CN | disclosed |
| US-20110159540-A1 | Methods for Chemically Synthesizing Immunoglobulin Chimeric Proteins | BIOVERATIV THERAPEUTICS INC. | 2011-06-30 | — | — | US | disclosed |
| US-20100105890-A1 | METHOD FOR PRODUCING FURANOSE DERIVATIVE | API CORPORATION (JP) | 2010-04-29 | — | — | US | disclosed |
| US-7642379-B2 | Aminoacetonitrile derivatives and their use for controlling parasites on warm-blooded animals | NOVARTIS AG (CH) | 2010-01-05 | — | — | US | disclosed |
| EP-2105445-A1 | METHOD FOR PRODUCTION OF FURANOSE DERIVATIVE | API Corporation (JP) | 2009-09-30 | — | — | EP | disclosed |
| US-20080194693-A1 | Aminoacetonitrile Derivatives and Their Use for Controlling Parasites on Warm-Blooded Animals | NOVARTIS AG (CH) | 2008-08-14 | — | — | US | disclosed |
| EP-1758849-A1 | AMINOACETONITRILE DERIVATIVES AND THEIR USE FOR CONTROLLING PARASITES ON WARM-BLOODED ANIMALS | Novartis AG (CH) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005121075-A1 | AMINOACETONITRILE DERIVATIVES AND THEIR USE FOR CONTROLLING PARASITES ON WARM-BLOODED ANIMALS | NOVARTIS AG (CH) | 2005-12-22 | — | — | WO | disclosed |
| US-5185320-A | Antibiotics | GRUPPO LEPETIT S.P.A. (IT) | 1993-02-09 | — | — | US | disclosed |
| EP-0391077-A1 | O56-alkyl derivatives of aglycone and pseudoaglycones of teicoplanin | GRUPPO LEPETIT S.p.A. (IT) | 1990-10-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220298164-A1 | ANTI-VIRAL DRUG | ZC3HAV1, ZC3HAV1L, SARS1 | MAOB 2946/4885CTSL 695/4885CTSB 2108/4885 |
| US-11370797-B2 | Anti-viral drug | NSUN3, EIF2AK2, NSUN2 | MAOB 3746/4885CTSL 3795/4885CTSB 3665/4885 |
| US-20080194693-A1 | Aminoacetonitrile Derivatives and Their Use for Controlling Parasites on Warm-Blooded Animals | MB, ACHE, ADORA2B | MAOB 203/4885CTSL 2448/4885CTSB 1739/4885 |
| US-20230150968-A1 | SUBSTITUTED THIOPHENE CARBOXAMIDES AND DERIVATIVES THEREOF AS MICROBICIDES | PGLS, MAVS, TPMT | MAOB 2146/4885CTSL 894/4885CTSB 604/4885 |
| US-20230132621-A1 | 1,5-DIHYDRO-2,4-BENZODIAZEPINE-3-ONE DERIVATIVE AND APPLICATION THEREOF | HTR2C, HTR2A, HTR2B | MAOB 259/4885CTSL 2807/4885CTSB 2175/4885 |
| US-20230046892-A1 | SUBSTITUTED THIOPHENE CARBOXAMIDES, THIOPHENE CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | PGLS, TST, TPI1 | MAOB 2438/4885CTSL 2317/4885CTSB 2005/4885 |
| US-20110159540-A1 | Methods for Chemically Synthesizing Immunoglobulin Chimeric Proteins | FCGR1A, FCGR2A, FCGR3B | MAOB 3752/4885CTSL 3133/4885CTSB 2301/4885 |
| US-20100105890-A1 | METHOD FOR PRODUCING FURANOSE DERIVATIVE | DERA, ALDOA, DPYD | MAOB 1223/4885CTSL 4066/4885CTSB 4229/4885 |
| US-20230055705-A1 | SUBSTITUTED THIOPHENE CARBOXAMIDES AND DERIVATIVES THEREOF | PGLS, TH, TST | MAOB 2377/4885CTSL 2769/4885CTSB 2511/4885 |
| US-12258349-B2 | Anti-viral drug | ZC3HAV1, ZC3HAV1L, SARS1 | MAOB 2946/4885CTSL 695/4885CTSB 2108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.