Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL333985 | 0.84 | SLC16A3 (0.40) | TNFRSF1A | |
| SCHEMBL6170009 | 0.65 | EGLN1 (0.42) | — | |
| SCHEMBL701444 | 0.65 | GPR35 (0.46) | ALDH1A1MAPTHPGDLMNATNFRSF1A | |
| SCHEMBL28910050 | 0.64 | PPARA (0.60) | MAPTLMNAHSD17B10TP53CYP2C9 | |
| SCHEMBL5186287 | 0.64 | PSEN1 (0.45) | ALDH1A1MAPTHPGDHSD17B10DYRK1A | |
| SCHEMBL6170913 | 0.64 | KMO (0.48) | ALDH1A1MAPTHPGDLMNAHSD17B10 | |
| SCHEMBL6225634 | 0.63 | TNFRSF1A (0.43) | ALDH1A1MAPTHPGDLMNATNFRSF1A | |
| SCHEMBL29037530 | 0.62 | HTR6 (0.45) | ALDH1A1MAPTHPGDHSD17B10ABCG2 | |
| SCHEMBL7813546 | 0.61 | HDAC6 (0.41) | — | |
| SCHEMBL6344994 | 0.61 | ALDH1A1 (0.50) | MPOALDH1A1MAPTHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298905-A1 | Nitrogenatd trans-stilbene analogs, method for the obtention and medical applications thereof | UNIVERSIDAD DEL PAIS VASCO (ES) | 2009-12-03 | — | — | US | claimed |
| US-8097656-B2 | Nitrogenated trans-stilbene analogs, method for the obtention and medical applications thereof | Dominion Pharmakine S.L (ES) | 2012-01-17 | — | — | US | disclosed |
| US-20110060038-A1 | NITROGENATED TRANS-STILBENE ANALOGS, METHOD FOR THE OBTENTION AND MEDICAL APPLICATIONS THEREOF | DOMINION PHARMAKINE S.L. (ES) | 2011-03-10 | — | — | US | disclosed |
| US-20090298905-A1 | Nitrogenatd trans-stilbene analogs, method for the obtention and medical applications thereof | UNIVERSIDAD DEL PAIS VASCO (ES) | 2009-12-03 | — | — | US | disclosed |
| EP-1874723-A2 | NEW NITROGENATED TRANS-STILBENE ANALOGS, METHOD FOR THE OBTENTION AND MEDICAL APPLICATIONS THEREOF | Dominion Pharmakine S.L. (ES) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006108864-A2 | NEW NITROGENATED TRANS-STILBENE ANALOGS, METHOD FOR THE OBTENTION AND MEDICAL APPLICATIONS THEREOF | DOMINION PHARMAKINE S.L. (ES) | 2006-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298905-A1 | Nitrogenatd trans-stilbene analogs, method for the obtention and medical applications thereof | TNNI3, TNNT2, INMT | MPO 255/4885ALDH1A1 250/4885MAPT 1864/4885 |
| US-20110060038-A1 | NITROGENATED TRANS-STILBENE ANALOGS, METHOD FOR THE OBTENTION AND MEDICAL APPLICATIONS THEREOF | TNNI3, TNNT2, NOS2 | MPO 350/4885ALDH1A1 370/4885MAPT 2027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.