Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16828345 | 0.78 | ALDH1A1 (0.34) | MEN1ALDH1A1HTTKMT2AHIF1A | |
| SCHEMBL5836235 | 0.74 | TTR (0.40) | ALDH1A1 | |
| SCHEMBL42660 | 0.73 | MEN1 (0.38) | MEN1ALDH1A1HTTKMT2AHIF1A | |
| SCHEMBL334886 | 0.68 | ALDH1A1 (0.35) | MEN1ALDH1A1HTTKMT2AHIF1A | |
| SCHEMBL16828348 | 0.66 | ALDH1A1 (0.36) | MAPK1MEN1ALDH1A1HTTKMT2A | |
| SCHEMBL14815405 | 0.64 | ALDH1A1 (0.53) | MEN1ALDH1A1KMT2A | |
| SCHEMBL20198678 | 0.63 | TSHR (0.32) | MAPK1ALDH1A1HIF1A | |
| SCHEMBL332010 | 0.61 | — | — | |
| SCHEMBL11859635 | 0.61 | MAPK1 (0.38) | MAPK1MEN1ALDH1A1KMT2A | |
| SCHEMBL4412 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE38947-E1 | Method of enantioselectively catalyzing a reaction | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 2006-01-24 | — | — | US | claimed |
| US-5296595-A | Metal complexes with bridging ligands | RESEARCH CORPORATION TECHNOLOGIES (US) | 1994-03-22 | — | — | US | claimed |
| US-9994595-B2 | Catalyst and battery components derived from condensation reactions with carba-closo-dodecaborate amines | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-06-12 | — | — | US | disclosed |
| US-20170084954-A1 | CATALYST AND BATTERY COMPONENTS DERIVED FROM CONDENSATION REACTIONS WITH CARBA-CLOSO-DODECABORATE AMINES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-03-23 | — | — | US | disclosed |
| WO-2015139060-A1 | CATALYST AND BATTERY COMPONENTS DERIVED FROM CONDENSATION REACTIONS WITH CARBA-CLOSO-DODECABORATE AMINES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-09-17 | — | — | WO | disclosed |
| US-8558017-B2 | Ruthenium (II) catalysts for use in stereoselective cyclopropanations | VANDA PHARMACEUTICALS, INC. (US) | 2013-10-15 | — | — | US | disclosed |
| US-20130023662-A9 | RUTHENIUM (II) CATALYSTS FOR USE IN STEREOSELECTIVE CYCLOPROPANATIONS | VANDA PHARMECEUTICALS INC. (US) | 2013-01-24 | — | — | US | disclosed |
| US-20120149906-A1 | RUTHENIUM (II) CATALYSTS FOR USE IN STEREOSELECTIVE CYCLOPROPANATIONS | VANDA PHARMECEUTICALS INC. (US) | 2012-06-14 | — | — | US | disclosed |
| US-8097738-B2 | Ruthenium (II) catalysts for use in stereoselective cyclopropanations | VANDA PHARMACEUTICALS INC. (US) | 2012-01-17 | — | — | US | disclosed |
| US-20100228039-A1 | RUTHENIUM (II) CATALYSTS FOR USE IN STEREOSELECTIVE CYCLOPROPANATIONS | VANDA PHARMECEUTICALS INC. (US) | 2010-09-09 | — | — | US | disclosed |
| US-7754902-B2 | Ruthenium(II) catalysts for use in stereoselective cyclopropanations | VANDA PHARMACEUTICALS, INC. (US) | 2010-07-13 | — | — | US | disclosed |
| US-20070270593-A1 | Ruthenium(II) catalysts for use in stereoselective cyclopropanations | R.P. SCHERER TECHNOLOGIES, INC. | 2007-11-22 | — | — | US | disclosed |
| US-RE38947-E1 | Method of enantioselectively catalyzing a reaction | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 2006-01-24 | — | — | US | disclosed |
| US-5296595-A | Metal complexes with bridging ligands | RESEARCH CORPORATION TECHNOLOGIES (US) | 1994-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149906-A1 | RUTHENIUM (II) CATALYSTS FOR USE IN STEREOSELECTIVE CYCLOPROPANATIONS | RUVBL2, SPR, RUVBL1 | MAPK1 4818/4885MEN1 4764/4885ALDH1A1 2164/4885 |
| US-20170084954-A1 | CATALYST AND BATTERY COMPONENTS DERIVED FROM CONDENSATION REACTIONS WITH CARBA-CLOSO-DODECABORATE AMINES | NUDC, NCAPH, C2CD5 | MAPK1 4483/4885MEN1 1795/4885ALDH1A1 4533/4885 |
| US-20130023662-A9 | RUTHENIUM (II) CATALYSTS FOR USE IN STEREOSELECTIVE CYCLOPROPANATIONS | RUVBL2, SPR, RUVBL1 | MAPK1 4818/4885MEN1 4764/4885ALDH1A1 2164/4885 |
| US-20100228039-A1 | RUTHENIUM (II) CATALYSTS FOR USE IN STEREOSELECTIVE CYCLOPROPANATIONS | RUVBL2, SPR, RUVBL1 | MAPK1 4818/4885MEN1 4764/4885ALDH1A1 2164/4885 |
| US-20070270593-A1 | Ruthenium(II) catalysts for use in stereoselective cyclopropanations | RUVBL2, SPR, RUVBL1 | MAPK1 4818/4885MEN1 4764/4885ALDH1A1 2164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.