Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42660 | 0.80 | MEN1 (0.38) | ALDH1A1MEN1HTTKMT2AHIF1A | |
| SCHEMBL16828345 | 0.73 | ALDH1A1 (0.34) | ALDH1A1MEN1HTTKMT2AHIF1A | |
| SCHEMBL7712185 | 0.71 | TSHR (0.45) | ALDH1A1HIF1ACTSK | |
| SCHEMBL248788 | 0.71 | — | — | |
| SCHEMBL334562 | 0.68 | MAPK1 (0.32) | ALDH1A1MEN1HTTKMT2AHIF1A | |
| SCHEMBL16828348 | 0.68 | ALDH1A1 (0.36) | ALDH1A1MEN1HTTKMT2AHIF1A | |
| SCHEMBL332010 | 0.67 | — | — | |
| SCHEMBL11007623 | 0.67 | MEN1 (0.30) | ALDH1A1MEN1HTTKMT2AHIF1A | |
| SCHEMBL809218 | 0.67 | TSHR (0.55) | ALDH1A1 | |
| SCHEMBL20361867 | 0.64 | GAA (0.44) | ALDH1A1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594608-B1 | CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS | RES CORP TECHNOLOGIES INC (US) | 1997-10-15 | — | — | EP | claimed |
| EP-0594608-A1 | CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS. | RES CORP TECHNOLOGIES INC (US) | 1994-05-04 | — | — | EP | claimed |
| EP-0594608-A4 | CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS. | RES CORP TECHNOLOGIES INC (US) | 1993-03-15 | — | — | EP | claimed |
| US-5175311-A | Reacting olefin with carbene precursor | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1992-12-29 | — | — | US | claimed |
| WO-1991014672-A1 | CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1991-10-03 | — | — | WO | claimed |
| US-9994595-B2 | Catalyst and battery components derived from condensation reactions with carba-closo-dodecaborate amines | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-06-12 | — | — | US | disclosed |
| US-20170084954-A1 | CATALYST AND BATTERY COMPONENTS DERIVED FROM CONDENSATION REACTIONS WITH CARBA-CLOSO-DODECABORATE AMINES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-03-23 | — | — | US | disclosed |
| WO-2015139060-A1 | CATALYST AND BATTERY COMPONENTS DERIVED FROM CONDENSATION REACTIONS WITH CARBA-CLOSO-DODECABORATE AMINES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-09-17 | — | — | WO | disclosed |
| US-8558017-B2 | Ruthenium (II) catalysts for use in stereoselective cyclopropanations | VANDA PHARMACEUTICALS, INC. (US) | 2013-10-15 | — | — | US | disclosed |
| US-20130023662-A9 | RUTHENIUM (II) CATALYSTS FOR USE IN STEREOSELECTIVE CYCLOPROPANATIONS | VANDA PHARMECEUTICALS INC. (US) | 2013-01-24 | — | — | US | disclosed |
| US-20120149906-A1 | RUTHENIUM (II) CATALYSTS FOR USE IN STEREOSELECTIVE CYCLOPROPANATIONS | VANDA PHARMECEUTICALS INC. (US) | 2012-06-14 | — | — | US | disclosed |
| US-8110699-B2 | Cobalt-catalyzed asymmetric cyclopropanation of alkenes with α-nitrodiazoacetates | UNIVERSITY OF SOUTH FLORIDA (US) | 2012-02-07 | — | — | US | disclosed |
| US-20100076239-A1 | ASYMMETRIC CYCLOPROPANATION OF ELECTRON-DEFICIENT OLEFINS WITH DIAZO REAGENTS | UNIVERSITY OF SOUTH FLORIDA (US) | 2010-03-25 | — | — | US | disclosed |
| US-20090069519-A1 | COBALT-CATALYZED ASYMMETRIC CYCLOPROPANATION OF ELECTRON-DEFICIENT OLEFINS | NATIONAL SCIENCE FOUNDATION | 2009-03-12 | — | — | US | disclosed |
| US-20070270593-A1 | Ruthenium(II) catalysts for use in stereoselective cyclopropanations | R.P. SCHERER TECHNOLOGIES, INC. | 2007-11-22 | — | — | US | disclosed |
| US-RE38947-E1 | Method of enantioselectively catalyzing a reaction | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 2006-01-24 | — | — | US | disclosed |
| EP-0594608-B1 | CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS | RES CORP TECHNOLOGIES INC (US) | 1997-10-15 | — | — | EP | disclosed |
| US-5296595-A | Metal complexes with bridging ligands | RESEARCH CORPORATION TECHNOLOGIES (US) | 1994-03-22 | — | — | US | disclosed |
| US-5175311-A | Reacting olefin with carbene precursor | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1992-12-29 | — | — | US | disclosed |
| US-4197408-A | COPPER COMPLEX CATALYST, 2,5-DIMETHYL-2,4-HEXADIEN) REACTED WITH DIAZOACETATE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149906-A1 | RUTHENIUM (II) CATALYSTS FOR USE IN STEREOSELECTIVE CYCLOPROPANATIONS | RUVBL2, SPR, RUVBL1 | ALDH1A1 2164/4885MEN1 4764/4885HTT 4034/4885 |
| US-20170084954-A1 | CATALYST AND BATTERY COMPONENTS DERIVED FROM CONDENSATION REACTIONS WITH CARBA-CLOSO-DODECABORATE AMINES | NUDC, NCAPH, C2CD5 | ALDH1A1 4533/4885MEN1 1795/4885HTT 967/4885 |
| US-20100076239-A1 | ASYMMETRIC CYCLOPROPANATION OF ELECTRON-DEFICIENT OLEFINS WITH DIAZO REAGENTS | DUOX2, DUOX1, PPOX | ALDH1A1 1047/4885MEN1 3493/4885HTT 1683/4885 |
| US-20130023662-A9 | RUTHENIUM (II) CATALYSTS FOR USE IN STEREOSELECTIVE CYCLOPROPANATIONS | RUVBL2, SPR, RUVBL1 | ALDH1A1 2164/4885MEN1 4764/4885HTT 4034/4885 |
| US-20070270593-A1 | Ruthenium(II) catalysts for use in stereoselective cyclopropanations | RUVBL2, SPR, RUVBL1 | ALDH1A1 2164/4885MEN1 4764/4885HTT 4034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.