Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.32 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL334739 | 0.78 | TGM2 (0.41) | ECE1KDM4ETGM2FAAHLMNA | |
| SCHEMBL18752932 | 0.73 | ECE1 (0.46) | ECE1KDM4EPLA2G2AHTTPRMT1 | |
| SCHEMBL9726421 | 0.71 | ECE1 (0.45) | ECE1KDM4EPLA2G2AHTTPRMT1 | |
| SCHEMBL35714 | 0.71 | TSHR (0.54) | ECE1KDM4EPLA2G2AHTTTGM2 | |
| SCHEMBL21836734 | 0.70 | ALDH1A1 (0.52) | ECE1LMNAEGLN1ALDH1A1 | |
| SCHEMBL543785 | 0.70 | ALDH1A1 (0.52) | ECE1LMNAEGLN1ALDH1A1 | |
| SCHEMBL543786 | 0.70 | ALDH1A1 (0.52) | ECE1LMNAEGLN1ALDH1A1 | |
| SCHEMBL20657235 | 0.68 | ECE1 (0.42) | ECE1KDM4EPLA2G2AHTTPRMT1 | |
| SCHEMBL21114363 | 0.67 | ECE1 (0.50) | ECE1KDM4EPLA2G2AHTTPRMT1 | |
| SCHEMBL440563 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE38947-E1 | Method of enantioselectively catalyzing a reaction | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 2006-01-24 | — | — | US | claimed |
| EP-0594608-B1 | CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS | RES CORP TECHNOLOGIES INC (US) | 1997-10-15 | — | — | EP | claimed |
| EP-0594608-A1 | CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS. | RES CORP TECHNOLOGIES INC (US) | 1994-05-04 | — | — | EP | claimed |
| US-5296595-A | Metal complexes with bridging ligands | RESEARCH CORPORATION TECHNOLOGIES (US) | 1994-03-22 | — | — | US | claimed |
| EP-0594608-A4 | CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS. | RES CORP TECHNOLOGIES INC (US) | 1993-03-15 | — | — | EP | claimed |
| WO-1991014672-A1 | CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1991-10-03 | — | — | WO | claimed |
| US-9994595-B2 | Catalyst and battery components derived from condensation reactions with carba-closo-dodecaborate amines | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-06-12 | — | — | US | disclosed |
| US-20170084954-A1 | CATALYST AND BATTERY COMPONENTS DERIVED FROM CONDENSATION REACTIONS WITH CARBA-CLOSO-DODECABORATE AMINES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-03-23 | — | — | US | disclosed |
| WO-2015139060-A1 | CATALYST AND BATTERY COMPONENTS DERIVED FROM CONDENSATION REACTIONS WITH CARBA-CLOSO-DODECABORATE AMINES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-09-17 | — | — | WO | disclosed |
| US-8558017-B2 | Ruthenium (II) catalysts for use in stereoselective cyclopropanations | VANDA PHARMACEUTICALS, INC. (US) | 2013-10-15 | — | — | US | disclosed |
| US-20130023662-A9 | RUTHENIUM (II) CATALYSTS FOR USE IN STEREOSELECTIVE CYCLOPROPANATIONS | VANDA PHARMECEUTICALS INC. (US) | 2013-01-24 | — | — | US | disclosed |
| US-20120149906-A1 | RUTHENIUM (II) CATALYSTS FOR USE IN STEREOSELECTIVE CYCLOPROPANATIONS | VANDA PHARMECEUTICALS INC. (US) | 2012-06-14 | — | — | US | disclosed |
| US-8110699-B2 | Cobalt-catalyzed asymmetric cyclopropanation of alkenes with α-nitrodiazoacetates | UNIVERSITY OF SOUTH FLORIDA (US) | 2012-02-07 | — | — | US | disclosed |
| US-20070270593-A1 | Ruthenium(II) catalysts for use in stereoselective cyclopropanations | R.P. SCHERER TECHNOLOGIES, INC. | 2007-11-22 | — | — | US | disclosed |
| US-RE38947-E1 | Method of enantioselectively catalyzing a reaction | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 2006-01-24 | — | — | US | disclosed |
| EP-0594608-B1 | CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS | RES CORP TECHNOLOGIES INC (US) | 1997-10-15 | — | — | EP | disclosed |
| EP-0594608-A1 | CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS. | RES CORP TECHNOLOGIES INC (US) | 1994-05-04 | — | — | EP | disclosed |
| US-5296595-A | Metal complexes with bridging ligands | RESEARCH CORPORATION TECHNOLOGIES (US) | 1994-03-22 | — | — | US | disclosed |
| EP-0594608-A4 | CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS. | RES CORP TECHNOLOGIES INC (US) | 1993-03-15 | — | — | EP | disclosed |
| US-5175311-A | Reacting olefin with carbene precursor | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1992-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149906-A1 | RUTHENIUM (II) CATALYSTS FOR USE IN STEREOSELECTIVE CYCLOPROPANATIONS | RUVBL2, SPR, RUVBL1 | ECE1 2763/4885KDM4E 1161/4885PLA2G2A 4439/4885 |
| US-20170084954-A1 | CATALYST AND BATTERY COMPONENTS DERIVED FROM CONDENSATION REACTIONS WITH CARBA-CLOSO-DODECABORATE AMINES | NUDC, NCAPH, C2CD5 | ECE1 4546/4885KDM4E 3391/4885PLA2G2A 1565/4885 |
| US-20130023662-A9 | RUTHENIUM (II) CATALYSTS FOR USE IN STEREOSELECTIVE CYCLOPROPANATIONS | RUVBL2, SPR, RUVBL1 | ECE1 2763/4885KDM4E 1161/4885PLA2G2A 4439/4885 |
| US-20070270593-A1 | Ruthenium(II) catalysts for use in stereoselective cyclopropanations | RUVBL2, SPR, RUVBL1 | ECE1 2763/4885KDM4E 1161/4885PLA2G2A 4439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.