Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.45 |
| ▸ | CA1 known ✓ | P00915 | 3/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 5/20 | 0.33 |
| ▸ | CES1 | P23141 | 4/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7752126 | 0.89 | CA2 (0.41) | CA2CA1GPR84ACE2 | |
| SCHEMBL7747690 | 0.89 | CA2 (0.41) | CA2CA1GPR84ACE2 | |
| SCHEMBL97487 | 0.89 | CA2 (0.41) | CA2CA1GPR84ACE2 | |
| SCHEMBL98813 | 0.89 | CA2 (0.41) | CA2CA1GPR84ACE2 | |
| SCHEMBL7751708 | 0.82 | FFAR1 (0.42) | FAAHCYP1A2KMT2AHSD17B10 | |
| SCHEMBL1007055 | 0.81 | FFAR4 (0.42) | CA2CA1GPR84MEN1KMT2A | |
| SCHEMBL8692682 | 0.80 | CA2 (0.47) | CA2CA1GPR84NFKB1ACE2 | |
| SCHEMBL99789 | 0.79 | CA2 (0.38) | CA2CA1GPR84NFKB1ACE2 | |
| SCHEMBL7885777 | 0.79 | FFAR4 (0.47) | GPR84MEN1KMT2AHSD17B10 | |
| SCHEMBL7752153 | 0.78 | KDM4C (0.34) | CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1703890-B1 | PEARLIZER CONCENTRATE AND ITS USE IN PERSONAL CARE COMPOSITIONS | RHODIA (US) | 2010-11-17 | — | — | EP | disclosed |
| US-7578995-B2 | Pearlizer concentrate and its use in personal care compositions | RHODIA INC. (US) | 2009-08-25 | — | — | US | disclosed |
| US-20080319090-A1 | Pearlizer concentrate and its use in personal care compositions | RHODIA INC. (US) | 2008-12-25 | — | — | US | disclosed |
| EP-1703890-A1 | PEARLIZER CONCENTRATE AND ITS USE IN PERSONAL CARE COMPOSITIONS | Rhodia Inc. (US) | 2006-09-27 | — | — | EP | disclosed |
| WO-2005070375-A1 | PEARLIZER CONCENTRATE AND ITS USE IN PERSONAL CARE COMPOSITIONS | RHODIA INC. (US) | 2005-08-04 | — | — | WO | disclosed |
| US-20050158270-A1 | Pearlizer concentrate and its use in personal care compositions | RHODIA INC. | 2005-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080319090-A1 | Pearlizer concentrate and its use in personal care compositions | CUTA, PHOSPHO1, PEX14 | CA2 2076/4885CA1 4034/4885GPR84 2535/4885 |
| US-20050158270-A1 | Pearlizer concentrate and its use in personal care compositions | CUTA, PHOSPHO1, PEX14 | CA2 2076/4885CA1 4034/4885GPR84 2535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.