Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.50 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.42 |
| ▸ | FDPS known ✓ | P14324 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3386052 | 1.00 | CA2 (0.50) | CA2RECQLGLAHPGDTSHR | |
| SCHEMBL3381883 | 0.98 | CA2 (0.47) | CA2RECQLGLAHPGDTSHR | |
| Potassium Ion SCHEMBL9280601 | 0.95 | CA2 (0.45) | CA2RECQLGLAHPGDTSHR | |
| Potassium Ion SCHEMBL10537891 | 0.95 | CA2 (0.45) | CA2RECQLGLAHPGDTSHR | |
| SCHEMBL17219439 | 0.86 | RECQL (0.47) | CA2RECQLGLAHPGDTSHR | |
| SCHEMBL8688848 | 0.86 | RECQL (0.47) | CA2RECQLGLAHPGDTSHR | |
| SCHEMBL9660940 | 0.86 | RECQL (0.47) | CA2RECQLGLAHPGDTSHR | |
| SCHEMBL9756753 | 0.86 | RECQL (0.47) | CA2RECQLGLAHPGDTSHR | |
| SCHEMBL28621358 | 0.86 | RECQL (0.47) | CA2RECQLGLAHPGDTSHR | |
| SCHEMBL17336061 | 0.86 | RECQL (0.47) | CA2RECQLGLAHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8900641-B2 | Antimicrobial composition | NALCO COMPANY (US) | 2014-12-02 | — | — | US | disclosed |
| EP-2097355-B1 | ANTIMICROBIAL COMPOSITION | NALCO CO (US) | 2012-07-04 | — | — | EP | disclosed |
| EP-1383462-B1 | COSMETIC COMPOSITIONS CONTAINING DISPERSION POLYMERS | ONDEO NALCO CO (US) | 2010-12-01 | — | — | EP | disclosed |
| WO-2010093847-A1 | ANTIMICROBIAL COMPOSITION | NALCO COMPANY (US) | 2010-08-19 | — | — | WO | disclosed |
| EP-2097355-A1 | ANTIMICROBIAL COMPOSITION | Nalco Company (US) | 2009-09-09 | — | — | EP | disclosed |
| US-20090214672-A1 | ANTIMICROBIAL COMPOSITION | ECOLAB USA INC. | 2009-08-27 | — | — | US | disclosed |
| WO-2008083263-A1 | ANTIMICROBIAL COMPOSITION | NALCO COMPANY (US) | 2008-07-10 | — | — | WO | disclosed |
| US-20080160104-A1 | ANTIMICROBIAL COMPOSITION | NALCO COMPANY | 2008-07-03 | — | — | US | disclosed |
| EP-1490581-A4 | USE OF DISPERSION POLYMERS AS FRICTION REDUCERS IN AQUEOUS FRACTURING FLUIDS | NALCO ENERGY SERVICES LP (US) | 2006-09-13 | — | — | EP | disclosed |
| EP-1490581-A1 | USE OF DISPERSION POLYMERS AS FRICTION REDUCERS IN AQUEOUS FRACTURING FLUIDS | Nalco Energy Services, L.P. (US) | 2004-12-29 | — | — | EP | disclosed |
| US-20030059382-A1 | Cosmetic compositions containing dispersion polymers | ECOLAB USA INC. | 2003-03-27 | — | — | US | disclosed |
| WO-2002083085-A1 | COSMETIC COMPOSITIONS CONTAINING DISPERSION POLYMERS | ONDEO NALCO COMPANY (US) | 2002-10-24 | — | — | WO | disclosed |
| EP-0929582-B1 | CATIONIC WATER-SOLUBLE POLYMER PRECIPITATION IN SALT SOLUTIONS | CYTEC TECH CORP (US) | 2001-11-14 | — | — | EP | disclosed |
| US-6013708-A | PRECIPITATING IN WATER SOLUTION COMPRISING AT LEAST ONE KOSMOTROPIC SALT, AND AT LEAST ONE ANIONIC ORGANIC SALT | CYTEC TECHNOLOGY CORP. (US) | 2000-01-11 | — | — | US | disclosed |
| US-5934839-A | CATIONIC POLYMER, ANIONIC ORGANIC SALT, KOSMOTROPIC SALT; SOIL CONDITIONERS | CYTECTECHNOLOGY CORP. (US) | 1999-08-10 | — | — | US | disclosed |
| EP-0929582-A1 | CATIONIC WATER-SOLUBLE POLYMER PRECIPITATION IN SALT SOLUTIONS | Cytec Technology Corp. (US) | 1999-07-21 | — | — | EP | disclosed |
| US-5885032-A | ADDING TO THE SOIL A SOIL CONDITIONING AMOUNT OF AQUEOUS SOLUTION CONTAINING A CHAOTROPIC SALT, A KESMOTROPIC SALT AND A PRECIPITATED CATIONIC WATER SOLUBLE POLYMER | CYTEC TECHNOLOGY CORP. (US) | 1999-03-23 | — | — | US | disclosed |
| US-5738794-A | Cationic water-soluble polymer preciptation in salt solutions | CYTEC TECHNOLOGY CORP. (US) | 1998-04-14 | — | — | US | disclosed |
| WO-1998014490-A1 | CATIONIC WATER-SOLUBLE POLYMER PRECIPITATION IN SALT SOLUTIONS | CYTEC TECHNOLOGY CORP. (US) | 1998-04-09 | — | — | WO | disclosed |
| US-5733462-A | FLOCCULATION, SOIL CONDITIONING, WASTE TREATMENT | CYTEC TECHNOLOGY CORP. (US) | 1998-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030059382-A1 | Cosmetic compositions containing dispersion polymers | POLR1C, NACA, TYR | CA2 3210/4885CA1 4395/4885FDPS 4028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.