SCHEMBL339623

SCHEMBL339623

CN(C)c1ccc2coc(-c3ccc(N4C(=O)C=CC4=O)cc3)c2c1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.39
MGLL Q99685 11/20 0.38
FAAH O00519 4/20 0.38
HSP90AA1 P07900 2/20 0.36
SNCA P37840 1/20 0.35
PGR P06401 1/20 0.34
TERT O14746 1/20 0.33
APP P05067 1/20 0.33
KDM4E B2RXH2 1/20 0.33
PKM P14618 1/20 0.33
MAPK1 P28482 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
RAD51 Q06609 1/20 0.33
ELANE P08246 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL339622 0.73 L3MBTL1 (0.51) EP300MGLLFAAHPGRAPP
SCHEMBL3759716 0.72 MGLL (0.65) MGLLFAAHHSP90AA1KDM4EPKM
SCHEMBL7750137 0.68 EP300 (0.78) EP300MGLLSNCAKDM4ETDP1
SCHEMBL27650867 0.67 MGLL (0.50) MGLLFAAHHSP90AA1KDM4EPKM
SCHEMBL3665727 0.66 MGLL (0.65) MGLLFAAHHSP90AA1PKMMAPK1
SCHEMBL458382 0.65 MGLL (0.52) MGLLFAAHHSP90AA1KDM4EPKM
SCHEMBL5150580 0.65 MGLL (0.52) MGLLFAAHSNCAAPPKDM4E
SCHEMBL8467655 0.65 HSP90AA1 (0.64) MGLLFAAHHSP90AA1KDM4EPKM
SCHEMBL4289960 0.65 MGLL (0.52) MGLLFAAHHSP90AA1KDM4EPKM
SCHEMBL23424170 0.64 MGLL (0.64) MGLLFAAHHSP90AA1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12638394-B2 Skin sensitization measuring reagent, method for measuring skin sensitization, and compound FUJIFILM CORPORATION (JP) 2026-05-26 US disclosed
EP-4036570-B1 REAGENT FOR MEASURING SKIN SENSITIZATION, METHOD FOR MEASURING SKIN SENSITIZATION, AND COMPOUND FUJIFILM CORP (JP) 2025-03-05 EP disclosed
EP-4234537-A1 REAGENT FOR MEASURING SKIN SENSITIZATION, COMPOUND, AND METHOD FOR MEASURING SKIN SENSITIZATION FUJIFILM Corporation (JP) 2023-08-30 EP disclosed
US-20230258569-A1 REAGENT FOR MEASURING SKIN SENSITIZATION, COMPOUND, AND METHOD FOR MEASURING SKIN SENSITIZATION FUJIFILM CORPORATION (JP) 2023-08-17 US disclosed
EP-4036570-A1 REAGENT FOR MEASURING SKIN SENSITIZATION, METHOD FOR MEASURING SKIN SENSITIZATION, AND COMPOUND FUJIFILM Corporation (JP) 2022-08-03 EP disclosed
US-20220214276-A1 SKIN SENSITIZATION MEASURING REAGENT, METHOD FOR MEASURING SKIN SENSITIZATION, AND COMPOUND FUJIFILM CORPORATION (JP) 2022-07-07 US disclosed
WO-2021060477-A1 REAGENT FOR MEASURING SKIN SENSITIZATION, METHOD FOR MEASURING SKIN SENSITIZATION, AND COMPOUND 富士フイルム株式会社 2021-04-01 WO disclosed
EP-1646395-B1 METHODS AND COMPOSITIONS FOR REGULATING LYMPHOCYTE ACTIVITY CURIS INC (US) 2014-11-05 EP disclosed
US-8637562-B2 Methods for detecting sulfhydryl-containing compounds in a biological test sample THERAVANCE, INC. (US) 2014-01-28 US disclosed
EP-2601048-A2 COMPOSITIONS AND METHODS FOR DETECTION OF SOILS ON FABRICS The Sun Products Corporation (US) 2013-06-12 EP disclosed
EP-1036092-A2 HYDROPHOBICALLY-MODIFIED PROTEIN COMPOSITIONS AND METHODS BIOGEN, INC. (US) 2000-09-20 EP disclosed
EP-1028741-A1 REGULATION OF EPITHELIAL TISSUE BY HEDGEHOG-LIKE POLYPEPTIDES, AND FORMULATIONS AND USES RELATED THERETO Ontogeny, Inc. (US) 2000-08-23 EP disclosed
WO-2000035948-A1 METHODS AND COMPOSITIONS FOR TREATING DISORDERS INVOLVING EXCITOTOXICITY BIOGEN, INC. (US) 2000-06-22 WO disclosed
EP-1009424-A2 REGULATION OF MUSCLE TISSUES BY HEDGEHOG-LIKE POLYPEPTIDES, AND FORMULATIONS AND USES RELATED THERETO Ontogeny, Inc. (US) 2000-06-21 EP disclosed
WO-2000027422-A2 METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING PERIPHERAL NEUROPATHIES BIOGEN, INC. (US) 2000-05-18 WO disclosed
WO-1999028343-A9 HYDROPHOBICALLY-MODIFIED PROTEIN COMPOSITIONS AND METHODS BIOGEN INC (US) 1999-10-14 WO disclosed
WO-1999028343-A2 HYDROPHOBICALLY-MODIFIED PROTEIN COMPOSITIONS AND METHODS BIOGEN, INC. (US) 1999-06-10 WO disclosed
WO-1999020298-A1 REGULATION OF EPITHELIAL TISSUE BY HEDGEHOG-LIKE POLYPEPTIDES, AND FORMULATIONS AND USES RELATED THERETO ONTOGENY, INC. (US) 1999-04-29 WO disclosed
WO-1999010004-A2 REGULATION OF MUSCLE TISSUES BY HEDGEHOG-LIKE POLYPEPTIDES, AND FORMULATIONS AND USES RELATED THERETO ONTOGENY, INC. (US) 1999-03-04 WO disclosed
US-5790627-A Method and apparatus for observing a specimen using an X-ray microscope RESEARCH DEVELOPMENT CORP. (JP) 1998-08-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12638394-B2 Skin sensitization measuring reagent, method for measuring skin sensitization, and compound HRH1, HRH4, CUTA EP300 4559/4885MGLL 3428/4885FAAH 1577/4885
US-20230258569-A1 REAGENT FOR MEASURING SKIN SENSITIZATION, COMPOUND, AND METHOD FOR MEASURING SKIN SENSITIZATION TST, CUTA, HNMT EP300 3897/4885MGLL 2570/4885FAAH 308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.