SCHEMBL340514

SCHEMBL340514

O=P(O)(c1ccc(Cl)cc1)c1ccc(Cl)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.56
TSHR P16473 3/20 0.56
MMP2 P08253 3/20 0.45
MMP8 P22894 2/20 0.45
MMP14 P50281 2/20 0.45
CYP2A6 P11509 1/20 0.44
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
MMP1 P03956 1/20 0.41
ALOX15 P16050 1/20 0.40
CA2 P00918 3/20 0.39
MAPT P10636 2/20 0.39
CA9 Q16790 2/20 0.39
CA14 Q9ULX7 2/20 0.39
CYP1A2 P05177 1/20 0.39
CA12 O43570 1/20 0.39
THRB P10828 1/20 0.39
PMP22 Q01453 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10809406 0.97 LMNA (0.54) LMNATSHRMMP2MMP8MMP14
SCHEMBL177262 0.83 CA2 (0.55) LMNATSHRMMP2MMP8MMP14
1,4-Dichlorobenzene SCHEMBL28425304 0.82 LMNA (0.57) LMNATSHRMMP2MMP8MMP14
SCHEMBL3398370 0.81 CA2 (0.52) LMNATSHRMMP2MMP8MMP14
Hydrochloric Acid SCHEMBL10916425 0.81 CA2 (0.52) LMNATSHRMMP2MMP8MMP14
SCHEMBL11389232 0.81 CA2 (0.52) LMNATSHRMMP2MMP8MMP14
SCHEMBL11655850 0.79 MEN1 (0.46) LMNATSHRMMP2MMP8MMP14
SCHEMBL11651162 0.79 MMP2 (0.42) LMNATSHRMMP2MMP8MMP14
SCHEMBL11813178 0.77 MMP2 (0.41) LMNATSHRMMP2MMP8MMP14
SCHEMBL1000520 0.77 LMNA (0.50) LMNATSHRMMP2MMP8MMP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109369716-B Aryl phosphine oxide compound and synthesis method and application thereof 广东工业大学 2021-12-10 CN disclosed
CN-111647105-B Carboxylic acid vinyl ester copolymer and preparation method thereof 中山大学 2021-09-14 CN disclosed
CN-111647105-A Carboxylic acid vinyl ester copolymer and preparation method thereof 中山大学 2020-09-11 CN disclosed
CN-109369716-A A kind of aryl oxidized phosphine compound and its synthetic method and application 广东工业大学 2019-02-22 CN disclosed
US-9822425-B2 Processes for recovering metals from aqueous solutions CYTEC TECHNOLOGY CORP. (US) 2017-11-21 US disclosed
US-9493494-B2 Phosphinine oxide derivative and preparation method thereof KNU-INDUSTRY COOPERATION FOUNDATION (KR) 2016-11-15 US disclosed
US-20150344506-A1 NOVEL PHOSPHININE OXIDE DERIVATIVE AND PREPARATION METHOD THEREOF KNU-INDUSTRY COOPERATION FOUNDATION (KR) 2015-12-03 US disclosed
US-20150135903-A1 PROCESSES FOR RECOVERING METALS FROM AQUEOUS SOLUTIONS CYTEC TECHNOLOGY CORP. (US) 2015-05-21 US disclosed
US-8968698-B2 Processes for recovering metals from aqueous solutions CYTEC TECHNOLOGY CORP. (US) 2015-03-03 US disclosed
US-20140127095-A1 PROCESSES FOR RECOVERING METALS FROM AQUEOUS SOLUTIONS CYTEC TECHNOLOGY CORP. (US) 2014-05-08 US disclosed
WO-2011005736-A2 PROCESSES FOR RECOVERING METALS FROM AQUEOUS SOLUTIONS CYTEC TECHNOLOGY CORP. (US) 2011-01-13 WO disclosed
US-20110005354-A1 PROCESSES FOR RECOVERING METALS FROM AQUEOUS SOLUTIONS CYTEC TECHNOLOGY CORP. (US) 2011-01-13 US disclosed
US-20100286316-A1 AMORPHOUS COMPOUND AND PRODUCTION METHOD THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed
EP-2246388-A1 Granular stabilizer formulation and production method thereof Sumitomo Chemical Company, Limited (JP) 2010-11-03 EP disclosed
EP-2239266-A1 Amorphous phosphite compound and method for its production Sumitomo Chemical Company, Limited (JP) 2010-10-13 EP disclosed
US-20100252943-A1 Method for producing granular composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-10-07 US disclosed
US-20100256267-A1 Method for producing granular composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-10-07 US disclosed
EP-2236552-A1 Method for producing granular composition Sumitomo Chemical Company, Limited (JP) 2010-10-06 EP disclosed
EP-2236551-A1 Method for producing granular composition Sumitomo Chemical Company, Limited (JP) 2010-10-06 EP disclosed
US-20100056680-A1 AMORPHOUS COMPOUND AND STABILIZER FOR POLYMERS CONTAINING THE AMORPHOUS COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286316-A1 AMORPHOUS COMPOUND AND PRODUCTION METHOD THEREOF CFD, GYS2, EDF1 LMNA 1824/4885TSHR 4818/4885MMP2 1256/4885
US-20100056680-A1 AMORPHOUS COMPOUND AND STABILIZER FOR POLYMERS CONTAINING THE AMORPHOUS COMPOUND RPS8, RPS23, RPS12 LMNA 4083/4885TSHR 2426/4885MMP2 2836/4885
US-20150344506-A1 NOVEL PHOSPHININE OXIDE DERIVATIVE AND PREPARATION METHOD THEREOF PHOSPHO1, PPIP5K2, ITPA LMNA 4841/4885TSHR 1319/4885MMP2 4731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.