Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 5/20 | 0.35 |
| ▸ | P2RY4 | P51582 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | PKLR | P30613 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21436270 | 0.88 | P2RY4 (0.37) | P2RY12P2RY4MEN1POLBKMT2A | |
| SCHEMBL4104253 | 0.84 | P2RY4 (0.40) | P2RY12P2RY4MEN1POLBKMT2A | |
| SCHEMBL21436640 | 0.82 | P2RY4 (0.37) | P2RY12P2RY4MEN1POLBKMT2A | |
| SCHEMBL21436543 | 0.82 | P2RY4 (0.40) | P2RY12P2RY4MEN1POLBKMT2A | |
| SCHEMBL4101684 | 0.82 | P2RY4 (0.38) | P2RY12P2RY4MEN1POLBKMT2A | |
| SCHEMBL10052604 | 0.81 | MEN1 (0.42) | P2RY12P2RY4MEN1POLBKMT2A | |
| SCHEMBL21436647 | 0.77 | P2RY4 (0.41) | P2RY12P2RY4MEN1POLBKMT2A | |
| SCHEMBL342250 | 0.76 | THRB (0.37) | P2RY12P2RY4MEN1POLBKMT2A | |
| SCHEMBL5410698 | 0.74 | P2RY4 (0.35) | P2RY12P2RY4MEN1POLBKMT2A | |
| SCHEMBL21436337 | 0.74 | P2RY4 (0.37) | P2RY12P2RY4MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3086762-B1 | ORAL CARE COMPOSITIONS WITH REDUCED SURFACE STAINING | COLGATE PALMOLIVE CO (US) | 2019-08-28 | — | — | EP | claimed |
| CN-105828785-B | The oral care composition of surface contamination with reduction | 高露洁-棕榄公司 | 2019-05-03 | — | — | CN | claimed |
| US-20160324753-A1 | ORAL CARE COMPOSITIONS WITH REDUCED SURFACE STAINING | COLGATE-PALMOLIVE COMPANY (US) | 2016-11-10 | — | — | US | claimed |
| EP-3086762-A1 | ORAL CARE COMPOSITIONS WITH REDUCED SURFACE STAINING | Colgate-Palmolive Company (US) | 2016-11-02 | — | — | EP | claimed |
| WO-2015100010-A1 | ORAL CARE COMPOSITIONS WITH REDUCED SURFACE STAINING | COLGATE-PALMOLIVE COMPANY (US) | 2015-07-02 | — | — | WO | claimed |
| EP-3691751-B1 | DUAL POLYMER COMPONENT HAIR COLORING COMPOSITION | WELLA OPERATIONS US LLC (US) | 2024-02-14 | — | — | EP | disclosed |
| US-20230310300-A1 | HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER | HFC PRESTIGE SERVICE GERMINY GMBH (DE) | 2023-10-05 | — | — | US | disclosed |
| EP-4171500-A1 | HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER | Wella Germany GmbH (DE) | 2023-05-03 | — | — | EP | disclosed |
| EP-2710996-B1 | Sunscreen compositions comprising colour pigments | BASF SE (DE) | 2022-08-17 | — | — | EP | disclosed |
| US-11384033-B2 | Compositions with improved urease-inhibiting effect comprising (thio)phosphoric acid triamide and further compounds such as amines and colorants | BASF SE (DE) | 2022-07-12 | — | — | US | disclosed |
| US-11324688-B2 | Bicomponent composition | WELLA INTERNATIONAL OPERATIONS SWI (CH) | 2022-05-10 | — | — | US | disclosed |
| US-20220054392-A1 | MULTICOMPONENT IN SITU COLORATION COMPOSITION | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2022-02-24 | — | — | US | disclosed |
| WO-2016103168-A1 | COMPOSITIONS WITH IMPROVED UREASE-INHIBITING EFFECT COMPRISING (THIO) PHOSPHORIC ACID TRIAMIDE AND FURTHER COMPOUNDS SUCH AS AMINES AND COLORANTS | BASF SE (DE) | 2016-06-30 | — | — | WO | disclosed |
| WO-2015100010-A1 | ORAL CARE COMPOSITIONS WITH REDUCED SURFACE STAINING | COLGATE-PALMOLIVE COMPANY (US) | 2015-07-02 | — | — | WO | disclosed |
| EP-2710996-A2 | Sunscreen compositions comprising colour pigments | BASF SE (DE) | 2014-03-26 | — | — | EP | disclosed |
| US-8268014-B2 | Hair dyeing composition | BASF SE Ludwigshafen (DE) | 2012-09-18 | — | — | US | disclosed |
| US-8257448-B2 | Hair dyeing composition | BASF SE (DE) | 2012-09-04 | — | — | US | disclosed |
| US-20120017931-A1 | HAIR DYEING COMPOSITION | BASF SE (DE) | 2012-01-26 | — | — | US | disclosed |
| US-20120012128-A1 | HAIR DYEING COMPOSITION | BASF SE (DE) | 2012-01-19 | — | — | US | disclosed |
| US-20110033400-A1 | SUNSCREEN COMPOSITIONS COMPRISING COLOUR PIGMENTS | BASF SE (US) | 2011-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120012128-A1 | HAIR DYEING COMPOSITION | CYC1, CYB5R3, TYR | P2RY12 4611/4885P2RY4 3823/4885MEN1 1913/4885 |
| US-20110033400-A1 | SUNSCREEN COMPOSITIONS COMPRISING COLOUR PIGMENTS | TYR, ERCC1, ERCC4 | P2RY12 3766/4885P2RY4 3656/4885MEN1 1447/4885 |
| US-20230310300-A1 | HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER | KRT18, MKI67, IK | P2RY12 4452/4885P2RY4 4027/4885MEN1 811/4885 |
| US-20120017931-A1 | HAIR DYEING COMPOSITION | CYB5R3, CYC1, CYCS | P2RY12 4644/4885P2RY4 3539/4885MEN1 2016/4885 |
| US-20220054392-A1 | MULTICOMPONENT IN SITU COLORATION COMPOSITION | KRT18, PRKDC, VIM | P2RY12 4739/4885P2RY4 4672/4885MEN1 1309/4885 |
| US-11324688-B2 | Bicomponent composition | KRT18, EXOSC10, EXOSC9 | P2RY12 3317/4885P2RY4 3269/4885MEN1 1869/4885 |
| US-11384033-B2 | Compositions with improved urease-inhibiting effect comprising (thio)phosphoric acid triamide and further compounds such as amines and colorants | SLC14A1, XDH, PNP | P2RY12 486/4885P2RY4 1162/4885MEN1 4263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.