Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 4/20 | 0.44 |
| ▸ | CA12 known ✓ | O43570 | 2/20 | 0.41 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | CASP6 | P55212 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NT5E | P21589 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 2/20 | 0.42 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29473550 | 1.00 | ALDH1A1 (0.58) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| Water SCHEMBL29627107 | 0.98 | ALDH1A1 (0.56) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL713915 | 0.86 | LMNA (0.47) | ALDH1A1HSD17B10CYP2C9CYP2C19TDP1 | |
| SCHEMBL342537 | 0.86 | ALDH1A1 (0.64) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL29702840 | 0.86 | ALDH1A1 (0.64) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL30461613 | 0.86 | LMNA (0.47) | ALDH1A1HSD17B10CYP2C9CYP2C19TDP1 | |
| SCHEMBL149375 | 0.86 | ALDH1A1 (0.64) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL1808981 | 0.85 | ALDH1A1 (0.48) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL29702707 | 0.85 | ALDH1A1 (0.53) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL142002 | 0.85 | ALDH1A1 (0.53) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986929-A | Room-temperature phosphorescent ink based on bio-based molecules-aromatic sulfonic acid or salts thereof, and preparation method and application thereof | 仲恺农业工程学院 | 2024-05-07 | — | — | CN | claimed |
| CN-115926860-A | Coal water slurry additive prepared by using industrial byproduct and preparation method thereof | 河北建新化工股份有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-113593931-B | Preparation method of supercapacitor electrode material NiCoMn-LDH/functionalized graphene | 燕山大学 | 2022-04-01 | — | — | CN | claimed |
| CN-113593931-A | Preparation method of supercapacitor electrode material NiCoMn-LDH/functionalized graphene | 燕山大学 | 2021-11-02 | — | — | CN | claimed |
| CN-109651839-B | Preparation method of orange reactive printing dye | 浙江劲光实业股份有限公司 | 2020-09-01 | — | — | CN | claimed |
| US-10468701-B2 | Multi-acid polymers from multifunctional amino acids and sulfonyl halide precursors and methods of making the same | NISSAN NORTH AMERICA, INC. (US) | 2019-11-05 | — | — | US | claimed |
| US-20170279145-A1 | MULTI-ACID POLYMERS FROM MULTIFUNCTIONAL AMINO ACIDS AND SULFONYL HALIDE PRECURSORS AND METHODS OF MAKING THE SAME | NISSAN MOTOR CO., LTD. (JP) | 2017-09-28 | — | — | US | claimed |
| CN-1169710-C | Process for preparing hydrogen sulfide | 唐培� | 2004-10-06 | — | — | CN | claimed |
| CN-1203886-A | Method for producing hydrogen sulfide | TANG PEISI (CN) | 1999-01-06 | — | — | CN | claimed |
| CN-112724349-B | Polymer and use thereof | 立邦涂料（中国）有限公司 | 2024-07-05 | — | — | CN | disclosed |
| US-20240167922-A1 | TRANSPARENTIZING REAGENT AND TRANSPARENTIZING METHOD | KYOTO UNIVERSITY (JP) | 2024-05-23 | — | — | US | disclosed |
| CN-117986929-A | Room-temperature phosphorescent ink based on bio-based molecules-aromatic sulfonic acid or salts thereof, and preparation method and application thereof | 仲恺农业工程学院 | 2024-05-07 | — | — | CN | disclosed |
| CN-114479106-B | Metal organic frame material with ammonia response and antibacterial functions and preparation method thereof | 桂林理工大学 | 2024-02-20 | — | — | CN | disclosed |
| EP-4306927-A1 | TRANSPARENTIZING REAGENT AND TRANSPARENTIZING METHOD | Kyoto University (JP) | 2024-01-17 | — | — | EP | disclosed |
| US-20060102047-A1 | Ink jet ink, ink jet recording method, ink cartridge, recording unit, and ink jet recording apparatus | CANON KABUSHIKI KAISHA (JP) | 2006-05-18 | — | — | US | disclosed |
| US-20060102046-A1 | Ink jet ink, ink set, ink jet recording method, ink cartridge, recording unit, and ink jet recording apparatus | CANON KABUSHIKI KAISHA (JP) | 2006-05-18 | — | — | US | disclosed |
| CN-1169710-C | Process for preparing hydrogen sulfide | 唐培� | 2004-10-06 | — | — | CN | disclosed |
| CN-1342600-A | Process for preparing hydrogen sulfide | TANG PEIKUN (CN) | 2002-04-03 | — | — | CN | disclosed |
| CN-1064023-C | Method for producing hydrogen sulfide | TANG PEISI (CN) | 2001-04-04 | — | — | CN | disclosed |
| CN-1203886-A | Method for producing hydrogen sulfide | TANG PEISI (CN) | 1999-01-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240167922-A1 | TRANSPARENTIZING REAGENT AND TRANSPARENTIZING METHOD | TST, TTR, ALB | CA2 2629/4885CA12 79/4885CA1 377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.