SCHEMBL343436

SCHEMBL343436

CCN(CC)c1cccc([C]=O)c1O

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
CYP3A4 P08684 1/20 0.38
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36
BRD4 O60885 1/20 0.31
CDK2 P24941 1/20 0.31
ALDH1A3 P47895 1/20 0.30
MEN1 O00255 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30
NOX1 Q9Y5S8 1/20 0.30
AR P10275 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5166248 0.81 AR (0.36) ALDH1A1CYP3A4ALDH1A3MEN1NPC1
SCHEMBL1980636 0.79 GAA (0.39) ALDH1A1GABRA1GABRB2
SCHEMBL19178163 0.77 ALDH1A3 (0.33) ALDH1A1CYP3A4ALDH1A3
SCHEMBL1914909 0.75 ALDH1A1 (0.38) ALDH1A1CYP3A4GABRA1GABRB2MEN1
SCHEMBL5680576 0.75 ALDH1A1 (0.46) ALDH1A1CYP3A4GABRA1GABRB2CDK2
SCHEMBL9162349 0.73 CA2 (0.38) ALDH1A1CYP3A4GABRA1GABRB2CDK2
SCHEMBL9765433 0.73 ALDH1A1 (0.52) ALDH1A1CYP3A4GABRA1GABRB2NPC1
SCHEMBL1982670 0.73 ERN1 (0.52) ALDH1A1CYP3A4GABRA1GABRB2BRD4
SCHEMBL5166923 0.71 HTR1A (0.35) ALDH1A1ALDH1A3MEN1NPC1RAB9A
SCHEMBL11308650 0.71 ALDH1A1 (0.52) ALDH1A1CYP3A4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 272 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3473237-B1 LIP COSMETIC SHISEIDO CO LTD (JP) 2023-04-19 EP claimed
EP-2523651-B1 WATER-RESISTANT COSMETIC FORMULATIONS COMPRISING A HYDROPHOBICALLY MODIFIED VINYLPYRROLIDONE COPOLYMER BASF SE (DE) 2020-03-11 EP claimed
EP-3236914-A1 SPRAYABLE COSMETIC SUNSCREEN COMPOSITION Spirig Pharma AG (CH) 2017-11-01 EP claimed
EP-2819643-B1 SUNSCREEN COMPOSITION COMPRISING UV COMPOSITE PROCTER & GAMBLE (US) 2017-10-18 EP claimed
EP-3038594-B1 SUNSCREEN FORMULATIONS COMPRISING GEMINI SURFACTANTS AND SILICONE BASED SURFACTANTS AKZO NOBEL CHEMICALS INT BV (NL) 2017-08-02 EP claimed
WO-2016102065-A1 SPRAYABLE COSMETIC SUNSCREEN COMPOSITION SPIRIG PHARMA AG (CH) 2016-06-30 WO claimed
EP-3024433-A1 TRANSPARENT SUNSCREEN COMPOSITIONS AND USE THEREOF SASOL Germany GmbH (DE) 2016-06-01 EP claimed
EP-2124934-B1 COSMETIC AND PHARMACEUTICAL APPLICATIONS OF N-ACETYLHYDROXYPROLINE BEIERSDORF AG (DE) 2015-04-08 EP claimed
WO-2015010679-A1 TRANSPARENT SUNSCREEN COMPOSITIONS AND USE THEREOF SASOL GERMANY GMBH (DE) 2015-01-29 WO claimed
EP-2368540-B1 TITANIUM OXIDE DISPERSION AND COSMETICS WHEREIN SAME IS BLENDED SHISEIDO CO LTD (JP) 2014-03-05 EP claimed
EP-2025324-B1 Method of Quenching Electronic Excitation of Chromophore-Containing Organic Molecules in Photoactive Compositions HALLSTAR INNOVATIONS CORP (US) 2013-08-14 EP claimed
EP-2334283-B1 RESILIENT PERSONAL CARE COMPOSITION COMPRISING POLYALKYL ETHER CONTAINING SILOXANE ELASTOMERS PROCTER & GAMBLE (US) 2013-02-27 EP claimed
US-20240225975-A9 AN IMPROVED LONG WEARING SUNSCREEN COSMETIC BASF SE (DE) 2024-07-11 US disclosed
US-20240225981-A1 Synthesized Molecule of Solketal Esters from Palm Kit Oil and Glycerin for Cosmetic and Agricultural Formulations NUOL GREEN CHEMISTRY LLC 2024-07-11 US disclosed
US-12023403-B2 Oil-in-water type emulsion cosmetics DOW TORAY CO., LTD. (JP) 2024-07-02 US disclosed
EP-3795138-B1 LIGHT AESTHETIC SUNSCREEN COMPOSITIONS JOHNSON & JOHNSON CONSUMER INC (US) 2024-05-15 EP disclosed
US-20070248632-A1 Highly Concentrated Self- Emulsifying Emulsion Bases Used for the Production of Oil-in-Water Emulsions COGNIS IP MANAGEMENT GMBH (DE) 2007-10-25 US disclosed
US-20070202060-A1 Retinoid-Containing Preparations BASF AKTIENGESELLSCHAFT PATENTS, TRADEMARKS AND LICENSES (DE) 2007-08-30 US disclosed
US-20060257338-A1 Novel photostabilizers, UV absorbers, and methods, of photostabilizing compositions CPH INNOVATIONS CORP. (US) 2006-11-16 US disclosed
US-20060002885-A1 Use of combinations of active ingredients of one or more bioquinones and one or more isoflavones for improving the contours of the skin BEIERSDORF AG (DE) 2006-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060002885-A1 Use of combinations of active ingredients of one or more bioquinones and one or more isoflavones for improving the contours of the skin CUTA, CYP19A1, DSG1 ALDH1A1 3983/4885CYP3A4 1145/4885GABRA1 3267/4885
US-20060257338-A1 Novel photostabilizers, UV absorbers, and methods, of photostabilizing compositions TTPA, ERCC1, ERCC4 ALDH1A1 339/4885CYP3A4 813/4885GABRA1 2585/4885
US-12023403-B2 Oil-in-water type emulsion cosmetics CUTA, MITF, POLQ ALDH1A1 3811/4885CYP3A4 4646/4885GABRA1 399/4885
US-20070202060-A1 Retinoid-Containing Preparations RBP1, RARB, RXRB ALDH1A1 147/4885CYP3A4 1767/4885GABRA1 1730/4885
US-20240225981-A1 Synthesized Molecule of Solketal Esters from Palm Kit Oil and Glycerin for Cosmetic and Agricultural Formulations DGKK, DGKA, DGKG ALDH1A1 1773/4885CYP3A4 2526/4885GABRA1 4115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.