SCHEMBL1914909

SCHEMBL1914909

CCN(CC)c1c(O)cccc1[C]=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
CYP3A4 P08684 1/20 0.38
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
CA14 Q9ULX7 1/20 0.34
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32
HTR1A P08908 1/20 0.32
THRB P10828 1/20 0.31
MEN1 O00255 3/20 0.31
KMT2A Q03164 3/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
HTR2A P28223 1/20 0.31
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30816668 0.80 ALDH1A1 (0.48) ALDH1A1CYP3A4CA12CA1CA2
SCHEMBL8538126 0.75 ALDH1A1 (0.38) ALDH1A1CYP3A4CA12CA1CA2
SCHEMBL343436 0.75 ALDH1A1 (0.38) ALDH1A1CYP3A4GABRA1GABRB2MEN1
SCHEMBL5166248 0.73 AR (0.36) ALDH1A1CYP3A4MEN1KMT2ASMN1; SMN2
SCHEMBL1953279 0.73 ALDH1A1 (0.42) ALDH1A1CYP3A4CA12CA1CA2
SCHEMBL3117753 0.73 TRPA1 (0.46) ALDH1A1CYP3A4CA12CA1CA2
SCHEMBL11332569 0.71 ERN1 (0.50) ALDH1A1CYP3A4CA1CA2THRB
SCHEMBL19178163 0.70 ALDH1A3 (0.33) ALDH1A1CYP3A4HTT
SCHEMBL1631930 0.69 TRPA1 (0.50) ALDH1A1CYP3A4CA12CA1CA2
SCHEMBL5166923 0.68 HTR1A (0.35) ALDH1A1HTR1AMEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3038594-B1 SUNSCREEN FORMULATIONS COMPRISING GEMINI SURFACTANTS AND SILICONE BASED SURFACTANTS AKZO NOBEL CHEMICALS INT BV (NL) 2017-08-02 EP claimed
EP-2124934-B1 COSMETIC AND PHARMACEUTICAL APPLICATIONS OF N-ACETYLHYDROXYPROLINE BEIERSDORF AG (DE) 2015-04-08 EP claimed
EP-2368540-B1 TITANIUM OXIDE DISPERSION AND COSMETICS WHEREIN SAME IS BLENDED SHISEIDO CO LTD (JP) 2014-03-05 EP claimed
US-12023403-B2 Oil-in-water type emulsion cosmetics DOW TORAY CO., LTD. (JP) 2024-07-02 US disclosed
US-20240148616-A1 WATER-IN-OIL EMULSION COMPOSITION, COSMETIC, AND METHOD FOR PREPARING WATER-IN-OIL EMULSION COMPOSITION SHISEIDO COMPANY, LTD. (JP) 2024-05-09 US disclosed
WO-2023079982-A1 SUNSCREEN COSMETIC 株式会社 資生堂 2023-05-11 WO disclosed
US-20220378674-A1 WATER-IN-OIL COSMETIC COMPOSITION WITH MAXIMIZED FEELING OF MOISTURE KOLMAR KOREA CO., LTD. (KR) 2022-12-01 US disclosed
US-20220362129-A1 COSMETIC SHISEIDO COMPANY, LTD. (JP) 2022-11-17 US disclosed
US-11413227-B2 Durable sunscreen cosmetic SHISEIDO COMPANY, LTD. (JP) 2022-08-16 US disclosed
US-20210330571-A1 OIL-IN-WATER TYPE EMULSION COSMETICS DOW TORAY CO., LTD. (JP) 2021-10-28 US disclosed
US-20210322296-A1 AQUEOUS DISPERSION COMPOSITION AND USE THEREOF DOW TORAY CO., LTD. (JP) 2021-10-21 US disclosed
CN-110121331-A Personal care compositions containing poorly soluble compounds 荷兰联合利华有限公司 2019-08-13 CN disclosed
US-20170172888-A1 Oil-in-Water Emulsion Cosmetic SHISEIDO COMPANY, LTD. (JP) 2017-06-22 US disclosed
EP-2515841-B1 COPOLYMER HAVING CARBOSILOXANE DENDRIMER STRUCTURE, AND COMPOSITION AND COSMETIC CONTAINING THE SAME DOW CORNING TORAY CO LTD (JP) 2016-12-21 EP disclosed
CN-106102697-A The solubilising of UV filtering agent 欧荔安公司 2016-11-09 CN disclosed
EP-2515841-A1 COPOLYMER HAVING CARBOSILOXANE DENDRIMER STRUCTURE, AND COMPOSITION AND COSMETIC CONTAINING THE SAME Dow Corning Toray Co., Ltd. (JP) 2012-10-31 EP disclosed
US-20120263662-A1 Copolymer Having Carbosiloxane Dendrimer Structure, And Composition And Cosmetic Containing The Same DOW TORAY CO., LTD. (JP) 2012-10-18 US disclosed
WO-2011078407-A1 COPOLYMER HAVING CARBOSILOXANE DENDRIMER STRUCTURE, AND COMPOSITION AND COSMETIC CONTAINING THE SAME DOW CORNING TORAY CO., LTD. (JP) 2011-06-30 WO disclosed
US-7358279-B2 Emulsions of oil-in-water for cosmetic and pharmaceutical compositions COGNIS IP MANAGEMENT GMBH (DE) 2008-04-15 US disclosed
US-20070248632-A1 Highly Concentrated Self- Emulsifying Emulsion Bases Used for the Production of Oil-in-Water Emulsions COGNIS IP MANAGEMENT GMBH (DE) 2007-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120263662-A1 Copolymer Having Carbosiloxane Dendrimer Structure, And Composition And Cosmetic Containing The Same TAS2R8, CUTA, TAS2R43 ALDH1A1 2522/4885CYP3A4 3855/4885CA12 2087/4885
US-20210322296-A1 AQUEOUS DISPERSION COMPOSITION AND USE THEREOF CUTA, ADH1A, ADH1C ALDH1A1 803/4885CYP3A4 2816/4885CA12 3727/4885
US-12023403-B2 Oil-in-water type emulsion cosmetics CUTA, MITF, POLQ ALDH1A1 3811/4885CYP3A4 4646/4885CA12 3823/4885
US-11413227-B2 Durable sunscreen cosmetic CUTA, POLR1C, SUN2 ALDH1A1 2213/4885CYP3A4 4306/4885CA12 4544/4885
US-20170172888-A1 Oil-in-Water Emulsion Cosmetic CUTA, CWC22, SCP2 ALDH1A1 3879/4885CYP3A4 4296/4885CA12 2761/4885
US-20210330571-A1 OIL-IN-WATER TYPE EMULSION COSMETICS CUTA, MITF, POLQ ALDH1A1 3900/4885CYP3A4 4662/4885CA12 3602/4885
US-20240148616-A1 WATER-IN-OIL EMULSION COMPOSITION, COSMETIC, AND METHOD FOR PREPARING WATER-IN-OIL EMULSION COMPOSITION CUTA, LAGE3, TES ALDH1A1 4519/4885CYP3A4 4604/4885CA12 1719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.