SCHEMBL344330

SCHEMBL344330

Cc1ccc(Nc2ccc(Nc3ccc(C)c(S(=O)(=O)O)c3)c3c2C(=O)c2ccccc2C3=O)cc1S(=O)(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GNG2 P59768 5/20 0.56
▸ GNB1 P62873 5/20 0.56
▸ PHLPP2 Q6ZVD8 2/20 0.53
▸ MET P08581 1/20 0.53
▸ P2RY4 P51582 6/20 0.53
▸ P2RY12 Q9H244 4/20 0.53
▸ P2RY2 P41231 3/20 0.53
▸ P2RY1 P47900 1/20 0.53
▸ P2RY6 Q15077 1/20 0.53
▸ CYP1A2 P05177 4/20 0.51
▸ HSD17B10 Q99714 3/20 0.51
▸ MAPK1 P28482 2/20 0.51
▸ CYP2C19 P33261 2/20 0.51
▸ HIF1A Q16665 2/20 0.51
▸ LMNA P02545 1/20 0.51
▸ CYP2C9 P11712 2/20 0.50
▸ ALOX15 P16050 2/20 0.50
▸ ALDH1A1 P00352 1/20 0.50
▸ CYP3A4 P08684 1/20 0.50
▸ HPGD P15428 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27585911 0.91 GNG2 (0.50) GNG2GNB1PHLPP2METP2RY4
SCHEMBL7743710 0.86 P2RY12 (0.53) GNG2GNB1METP2RY4P2RY12
SCHEMBL14022702 0.85 GNG2 (0.53) GNG2GNB1PHLPP2METP2RY4
SCHEMBL8697325 0.83 P2RY12 (0.50) GNG2GNB1METP2RY4P2RY12
SCHEMBL14584437 0.83 GNG2 (0.50) GNG2GNB1PHLPP2METP2RY4
SCHEMBL20520387 0.83 MAPT (0.54) GNG2GNB1METP2RY4P2RY12
SCHEMBL20333921 0.81 MAPT (0.59) GNG2GNB1PHLPP2P2RY4P2RY12
SCHEMBL9136312 0.80 GNG2 (0.75) GNG2GNB1PHLPP2METP2RY4
SCHEMBL13213997 0.80 P2RY12 (0.79) GNG2GNB1PHLPP2METP2RY4
SCHEMBL11443152 0.79 GNG2 (0.73) GNG2GNB1PHLPP2METP2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4739489-A1 COMPOSITES FORMED USING LEWIS-ACID POLYMERIZED POLYOLS AND METHODS OF PREPARING SAME Dow Global Technologies LLC (US) 2026-05-13 — — EP disclosed
US-20250019555-A1 INK COMPOSITION FOR SURFACE PRINTING ON COSMETICS, AND METHOD FOR SURFACE PRINTING ON COSMETICS BY USING SAME ACTIVON CO., LTD. (KR) 2025-01-16 — — US disclosed
WO-2025007334-A1 COMPOSITES FORMED USING LEWIS-ACID POLYMERIZED POLYOLS AND METHODS OF PREPARING SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2025-01-09 — — WO disclosed
EP-3906009-B1 MOUSSE-LIKE COSMETIC PREPARATION BEIERSDORF AG (DE) 2024-12-18 — — EP disclosed
EP-4442774-A1 INK COMPOSITION FOR SURFACE PRINTING ON COSMETICS, AND METHOD FOR SURFACE PRINTING ON COSMETICS BY USING SAME Activon Co., Ltd. (KR) 2024-10-09 — — EP disclosed
WO-2024011530-A1 COLORIMETRIC CURING INDICATORS IN POLYURETHANE ACRYLATE HYBRID RESIN SYSTEMS AND METHODS OF USING SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2024-01-18 — — WO disclosed
WO-2023195319-A1 POSITIVE PHOTOSENSITIVE PIGMENT COMPOSITION, CURED FILM CONTAINING CURED PRODUCT THEREOF, AND ORGANIC EL DISPLAY DEVICE 東レ株式会社 2023-10-12 — — WO disclosed
US-20170105910-A1 UV FILTER CAPSULE BASF SE (DE) 2017-04-20 — — US disclosed
US-9084734-B2 Peptide personal care compositions and methods for their use DANISCO US INC. (US) 2015-07-21 — — US disclosed
US-8962796-B2 Modified variant Bowman Birk protease inhibitors DANISCO US INC. (US) 2015-02-24 — — US disclosed
US-20060194057-A1 Silicon dioxide-coated nanoparticulate uv protectant MERCK PATENT GMBH (DE) 2006-08-31 — — US disclosed
US-7037511-B1 Hydrous cosmetic or pharmaceutical sticks BEIERSDORF AG (DE) 2006-05-02 — — US disclosed
US-20060045856-A1 Composition containing a dihydroxyacetone precursor MERCK PATENT GMBH (DE) 2006-03-02 — — US disclosed
US-20060039937-A1 Composition having antioxidant properties MERCK PATENT GMBH (DE) 2006-02-23 — — US disclosed
US-20060002875-A1 Diffractive colorants for cosmetics MERCK PATENT GMBH (DE) 2006-01-05 — — US disclosed
US-20050276764-A1 Topical use of bis-arylimidazo[1,2-a]thiolane derivatives BEIERSDORF AG 2005-12-15 — — US disclosed
US-20050120917-A1 Coloured microstructured effect pigments MERCK PATENT GMBH (DE) 2005-06-09 — — US disclosed
US-20050074471-A1 Self-foaming or foamy preparations comprising particulate hydrophobic and/or hydrophobized and/or oil-absorbent solid substances BEIERSDORF AG (DE) 2005-04-07 — — US disclosed
US-20050002994-A1 Cosmetic or dermatological impregnated tissues BEIERSDORF AG (DE) 2005-01-06 — — US disclosed
US-6620420-B2 Cosmetic or dermatological application BEIERSDORF AG (DE) 2003-09-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050074471-A1 Self-foaming or foamy preparations comprising particulate hydrophobic and/or hydrophobized and/or oil-absorbent solid substances HBB, HBG1, FFAR1 GNG2 1472/4885GNB1 619/4885PHLPP2 2869/4885
US-20060039937-A1 Composition having antioxidant properties GPX4, GPX1, CAT GNG2 3463/4885GNB1 4162/4885PHLPP2 1960/4885
US-20060002875-A1 Diffractive colorants for cosmetics RARA, RARG, DSG1 GNG2 1022/4885GNB1 2281/4885PHLPP2 3015/4885
US-20170105910-A1 UV FILTER CAPSULE UROD, MITF, NISCH GNG2 1933/4885GNB1 3005/4885PHLPP2 2960/4885
US-20060045856-A1 Composition containing a dihydroxyacetone precursor TYR, CUTA, DERA GNG2 2721/4885GNB1 2427/4885PHLPP2 4380/4885
US-20050276764-A1 Topical use of bis-arylimidazo[1,2-a]thiolane derivatives ITCH, TRPA1, TPH1 GNG2 2256/4885GNB1 1508/4885PHLPP2 850/4885
US-20050002994-A1 Cosmetic or dermatological impregnated tissues CUTA, KAT8, PWWP2B GNG2 3406/4885GNB1 2849/4885PHLPP2 685/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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