SCHEMBL345987

SCHEMBL345987

C=C(C)C(=O)OCCC(OC(=O)CCC(=O)O)C(COC(=O)C(=C)C)OC(=O)c1ccc(C(=O)O)c(C(=O)O)c1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.36
APEX1 P27695 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ALDH1A1 P00352 2/20 0.31
KDM4E B2RXH2 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28622124 0.90 POLB (0.37) POLBAPEX1HTTTDP1ALDH1A1
SCHEMBL7084792 0.79 POLB (0.41) POLBAPEX1HTTTDP1ALDH1A1
SCHEMBL10715846 0.78 POLB (0.45) POLBAPEX1HTTTDP1ALDH1A1
SCHEMBL5846246 0.77 PTPN1 (0.48) POLBAPEX1HTTTDP1ALDH1A1
SCHEMBL29657635 0.76 POLB (0.49) POLBAPEX1HTTTDP1ALDH1A1
SCHEMBL33378 0.75 PTPN1 (0.52) POLBAPEX1HTTTDP1ALDH1A1
SCHEMBL7126886 0.75 POLB (0.40) POLBAPEX1HTTTDP1ALDH1A1
SCHEMBL837846 0.74 POLB (0.50) POLBAPEX1HTTTDP1ALDH1A1
SCHEMBL8373670 0.73 ADRB2 (0.41) POLBAPEX1HTTTDP1ALDH1A1
SCHEMBL11228078 0.72 TDP1 (0.54) POLBAPEX1HTTTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8329845-B2 Divided redox-curing type composition KURARAY NORITAKE DENTAL INC. (JP) 2012-12-11 US claimed
WO-2024150826-A1 DENTAL COMPOSITION クラレノリタケデンタル株式会社 2024-07-18 WO disclosed
EP-3848418-B1 DENTAL CURABLE COMPOSITION AND METHOD FOR PRODUCING DENTAL CURABLE COMPOSITION TOKUYAMA DENTAL CORP (JP) 2024-05-22 EP disclosed
EP-4360609-A1 DENTAL ADHESIVE KIT Kuraray Noritake Dental Inc. (JP) 2024-05-01 EP disclosed
US-20240091107-A1 DENTAL COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2024-03-21 US disclosed
WO-2024053223-A1 CARIOUS TOOTH STRUCTURE RECOVERY AGENT, AND DENTAL ADHESIVE KIT クラレノリタケデンタル株式会社 2024-03-14 WO disclosed
US-20240074946-A1 DENTAL COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2024-03-07 US disclosed
WO-2024043291-A1 DENTAL ADHESIVE COMPOSITION クラレノリタケデンタル株式会社 2024-02-29 WO disclosed
EP-3936109-B1 SOLVENT-FREE ADHESIVE COMPOSITION FOR DENTAL USE KURARAY NORITAKE DENTAL INC (JP) 2024-02-14 EP disclosed
US-20230390163-A1 DENTAL COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2023-12-07 US disclosed
EP-1459726-A1 ADHESIVES FOR DENTAL USE TOKUYAMA CORPORATION (JP) 2004-09-22 EP disclosed
EP-1431315-A2 Photopolymerization initiator and photopolymerizable composition Tokuyama Corporation (JP) 2004-06-23 EP disclosed
US-20040077746-A1 Adhesives for dental use TOKUYAMA CORPORATION (JP) 2004-04-22 US disclosed
JP-2004026838-A DENTAL ADHESION KIT TOKUYAMA CORP 2004-01-29 JP disclosed
US-20040006154-A1 Deantal catalyst for chemical polymerization and use thereof IBARAGI KAZUYA (JP) 2004-01-08 US disclosed
US-20020132951-A1 Dental catalyst for chemical polymerization and use thereof TOKUYAMA CORPORATION 2002-09-19 US disclosed
EP-1190695-A1 Catalyst for chemical polymerization of dental materials TOKUYAMA CORPORATION (JP) 2002-03-27 EP disclosed
EP-0712622-B1 Dental composition and kit TOKUYAMA CORP (JP) 1999-09-01 EP disclosed
US-5925690-A UNSATURATED PHOSPHATE AND UNSATURATED POLYCARBOXYLIC ACID MONOMERS; BONDING AND TENSILE STRENGTH TO DENTIN AND ENAMEL TOKUYAMA CORPROATION (JP) 1999-07-20 US disclosed
EP-0712622-A1 Dental composition and kit TOKUYAMA CORPORATION (JP) 1996-05-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240074946-A1 DENTAL COMPOSITION PIEZO1, TAS2R42, EIF2B3 POLB 589/4885APEX1 2093/4885HTT 1523/4885
US-20040006154-A1 Deantal catalyst for chemical polymerization and use thereof MPO, DBN1, BRD1 POLB 375/4885APEX1 98/4885HTT 144/4885
US-20040077746-A1 Adhesives for dental use ICAM1, CDH1, VCAM1 POLB 4097/4885APEX1 988/4885HTT 2631/4885
US-20240091107-A1 DENTAL COMPOSITION CCT7, TAS2R42, CCT5 POLB 684/4885APEX1 1011/4885HTT 1491/4885
US-20230390163-A1 DENTAL COMPOSITION CAD, TAS2R42, SMCHD1 POLB 1325/4885APEX1 390/4885HTT 895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.