SCHEMBL3476595

SCHEMBL3476595

O=C(O)c1ccc(NC2CCCCC2)cc1

nearest known ligand 0.62

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HCAR3 P49019 5/20 0.58
MERTK Q12866 1/20 0.52
EPHX2 P34913 2/20 0.50
LMNA P02545 1/20 0.50
POLB P06746 1/20 0.50
GAA P10253 1/20 0.50
MAPT P10636 1/20 0.50
SRD5A2 P31213 1/20 0.50
LTA4H P09960 2/20 0.48
TRPV1 Q8NER1 1/20 0.48
RAB9A P51151 2/20 0.47
NPC1 O15118 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
EPHX1 P07099 1/20 0.47
STS P08842 1/20 0.47
KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11478987 1.00 HCAR3 (0.58) HCAR3MERTKEPHX2LMNAPOLB
SCHEMBL11460577 1.00 HCAR3 (0.58) HCAR3MERTKEPHX2LMNAPOLB
SCHEMBL11465510 1.00 HCAR3 (0.58) HCAR3MERTKEPHX2LMNAPOLB
SCHEMBL11461585 1.00 HCAR3 (0.58) HCAR3MERTKEPHX2LMNAPOLB
SCHEMBL1663449 0.98 HCAR3 (0.60) HCAR3MERTKEPHX2LMNAPOLB
SCHEMBL28691867 0.94 HCAR3 (0.60) HCAR3MERTKEPHX2LMNAPOLB
SCHEMBL11462469 0.92 HCAR3 (0.51) HCAR3MERTKEPHX2LMNAPOLB
SCHEMBL11462467 0.92 HCAR3 (0.51) HCAR3MERTKEPHX2LMNAPOLB
SCHEMBL1542507 0.90 HCAR3 (0.58) HCAR3MERTKLMNASRD5A2LTA4H
SCHEMBL4940251 0.87 LMNA (0.51) HCAR3EPHX2LMNAPOLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110313158-A1 Two Component Recyclable Heterogeneous Catalyst, Process for Preparation Thereof and its Use for Preparation of Amines COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2011-12-22 US claimed
WO-2010097815-A2 A TWO COMPONENT RECYCLABLE HETEROGENEOUS CATALYST, PROCESS FOR PREPARATION THEREOF AND ITS USE FOR PREPARATION OF AMINES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2010-09-02 WO claimed
US-4227014-A ANTILIPEMIC AGENTS, ANTIATHEROSCLEROTIC AGENTS AMERICAN CYANAMID COMPANY (US) 1980-10-07 US claimed
US-12297209-B2 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2025-05-13 US disclosed
WO-2025086591-A1 ROTIGOTINE PRODRUG DERIVATIVE, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF 烟台药物研究所 2025-05-01 WO disclosed
US-12268694-B2 Combination pharmaceutical agents as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2025-04-08 US disclosed
US-20240360155-A1 Benzodiazepine Derivatives as RSV Inhibitors ENANTA PHARM INC (US) 2024-10-31 US disclosed
US-11952389-B2 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2024-04-09 US disclosed
EP-3687543-B1 COMBINATIONS OF PHARMACEUTICAL AGENTS AS RSV INHIBITORS ENANTA PHARM INC (US) 2024-03-20 EP disclosed
CN-111386118-B Combination pharmaceutical agents as RSV inhibitors 英安塔制药有限公司 2023-05-09 CN disclosed
US-20230087410-A1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS ENANTA PHARM INC (US) 2023-03-23 US disclosed
WO-2015042561-A1 THERMOPLASTIC POLYMER COMPOSITION MILLIKEN & COMPANY (US) 2015-03-26 WO disclosed
US-20150087758-A1 THERMOPLASTIC POLYMER COMPOSITION MILLIKEN & COMPANY 2015-03-26 US disclosed
US-20110313158-A1 Two Component Recyclable Heterogeneous Catalyst, Process for Preparation Thereof and its Use for Preparation of Amines COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2011-12-22 US disclosed
WO-2010097815-A2 A TWO COMPONENT RECYCLABLE HETEROGENEOUS CATALYST, PROCESS FOR PREPARATION THEREOF AND ITS USE FOR PREPARATION OF AMINES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2010-09-02 WO disclosed
EP-1719773-B1 FUSED HETEROTETRACYCLIC COMPOUNDS AND USE TEHREOF AS HCV POLYMERASE INHIBITOR JAPAN TOBACCO INC (JP) 2009-04-15 EP disclosed
US-4423051-A ANTIATHEROSCLEROTIC AGENTS AND HYPOLIPIDEMIC AGENTS AMERICAN CYANAMID COMPANY (US) 1983-12-27 US disclosed
US-4227014-A ANTILIPEMIC AGENTS, ANTIATHEROSCLEROTIC AGENTS AMERICAN CYANAMID COMPANY (US) 1980-10-07 US disclosed
EP-0003663-A2 Amino-substituted phenyl and heteroaryl compounds, process for their preparation and pharmaceutical compositions containing them AMERICAN CYANAMID COMPANY (US) 1979-08-22 EP disclosed
US-4105791-A Hypolipidemic cycloalkylaminobenzoic acids THE DOW CHEMICAL COMPANY (US) 1978-08-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240360155-A1 Benzodiazepine Derivatives as RSV Inhibitors GABRA5, GABRA1, GABBR2 HCAR3 725/4885MERTK 2798/4885EPHX2 1891/4885
US-11952389-B2 Benzodiazepine derivatives as RSV inhibitors GABRA5, GABRA1, GABBR2 HCAR3 725/4885MERTK 2798/4885EPHX2 1891/4885
US-12297209-B2 Benzodiazepine derivatives as RSV inhibitors GABRA5, GABRA1, GABBR2 HCAR3 725/4885MERTK 2798/4885EPHX2 1891/4885
US-20230087410-A1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS GABRA5, GABRA1, GABBR2 HCAR3 725/4885MERTK 2798/4885EPHX2 1891/4885
US-20110313158-A1 Two Component Recyclable Heterogeneous Catalyst, Process for Preparation Thereof and its Use for Preparation of Amines HCN2, RAC2, HCN1 HCAR3 2694/4885MERTK 4004/4885EPHX2 121/4885
US-12268694-B2 Combination pharmaceutical agents as RSV inhibitors ACE, ACE2, SPCS3 HCAR3 2461/4885MERTK 3551/4885EPHX2 4072/4885
US-20150087758-A1 THERMOPLASTIC POLYMER COMPOSITION ERCC4, SMCHD1, XRCC5 HCAR3 4564/4885MERTK 4717/4885EPHX2 759/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.