Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 5/20 | 0.50 |
| ▸ | CA2 known ✓ | P00918 | 5/20 | 0.50 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.50 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL7513559 | 0.95 | CA1 (0.50) | CA1CA2CA7CA9CA12 | |
| Potassium Ion SCHEMBL7514700 | 0.95 | CA1 (0.50) | CA1CA2CA7CA9CA12 | |
| Silver SCHEMBL11297956 | 0.95 | CA1 (0.50) | CA1CA2CA7CA9CA12 | |
| Lithium Ion SCHEMBL6326431 | 0.90 | ESR2 (0.47) | CA1CA2CA7CA9CA12 | |
| SCHEMBL9797562 | 0.81 | ALDH1A1 (0.39) | ALDH1A1TDP1MAPK1MAPTMMP2 | |
| Water SCHEMBL11855974 | 0.79 | ALDH1A1 (0.38) | ALDH1A1TDP1MAPK1MAPTMMP2 | |
| SCHEMBL28504519 | 0.77 | CA1 (0.50) | CA1CA2CA7CA9CA12 | |
| SCHEMBL11073462 | 0.77 | ALDH1A1 (0.50) | CA1CA2ALDH1A1CYP2A6CYP3A4 | |
| SCHEMBL11412919 | 0.76 | SMN1; SMN2 (0.36) | ALDH1A1TDP1MAPK1MAPTMMP2 | |
| SCHEMBL28523196 | 0.75 | LMNA (0.53) | CA9CA12PKMALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120136752-A | Alkenyl substituted tellurium organic compound, preparation method and application thereof in resisting plant pathogenic bacteria | 贵州大学 | 2025-06-13 | — | — | CN | claimed |
| CN-112010723-B | Method for preparing diaryl methyl substituted thioether | 湖南理工学院 | 2022-08-19 | — | — | CN | claimed |
| US-9650330-B2 | Process for the synthesis of aryl sulfones | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2017-05-16 | — | — | US | claimed |
| US-20160304447-A1 | A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-10-20 | — | — | US | claimed |
| WO-2015087352-A1 | A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-06-18 | — | — | WO | claimed |
| EP-4646402-A1 | GPR35 MODULATORS | ThirtyFiveBio Limited (GB) | 2025-11-12 | — | — | EP | disclosed |
| CN-120136752-A | Alkenyl substituted tellurium organic compound, preparation method and application thereof in resisting plant pathogenic bacteria | 贵州大学 | 2025-06-13 | — | — | CN | disclosed |
| CN-120060869-A | Electrocatalytic synthesis method of aryl sulfone compound | 平顶山学院 | 2025-05-30 | — | — | CN | disclosed |
| CN-117567347-B | Method for synthesizing indolyl benzyl sulfone compound by photocatalysis | 南京工业大学 | 2025-05-02 | — | — | CN | disclosed |
| CN-118930466-A | Alkynyl thiosulfonate with photosensitivity and thermal stability and preparation method thereof | 太原理工大学 | 2024-11-12 | — | — | CN | disclosed |
| CN-118359525-A | Se-deuterated methyl-arylsulfonyl selenate compound and synthetic method and application thereof | 浙江工业大学 | 2024-07-19 | — | — | CN | disclosed |
| CN-116082204-B | Beta-sulfinyl alkenyl sulfone compound and preparation method and application thereof | 华南师范大学 | 2024-07-12 | — | — | CN | disclosed |
| EP-0055474-B1 | THE USE OF BETA-SULFONYLACRYLIC ACID DERIVATIVES ON A DRY BLEND CONTAINING THEM OR PELLETS MADE THEREFROM IN SYNTHETIC POLYMERS | STAUFFER CHEMICAL COMPANY (US) | 1986-04-30 | — | — | EP | disclosed |
| US-4388249-A | PROTECTION OF PLASTICS AGAINST ATTACK BY MICROORGANISMS | STAUFFER CHEMICAL COMPANY (US) | 1983-06-14 | — | — | US | disclosed |
| US-4331480-A | 3-(4-METHOXYPHENYL SULFONYL) ACRYLONITRILE AND DERIVATIVES; BACTERICIDES; FUNGICIDES) ALGICIDES | STAUFFER CHEMICAL COMPANY (US) | 1982-05-25 | — | — | US | disclosed |
| US-4301278-A | BY HYDROGENATION IN THE PRESENCE OF A CATALYST | CIBA-GEIGY CORPORATION (US) | 1981-11-17 | — | — | US | disclosed |
| US-4255328-A | CEPHALOSPORINS | CIBA-GEIGY CORPORATION (US) | 1981-03-10 | — | — | US | disclosed |
| US-4147864-A | Process for the manufacture of 7β-amino-3-cephem-3-ol-4 carboxylic acid compounds | CIBA-GEIGY CORPORATION (US) | 1979-04-03 | — | — | US | disclosed |
| US-4049718-A | Sulphones | RHONE-POULENC, S.A. (FR) | 1977-09-20 | — | — | US | disclosed |
| US-4048234-A | Sulphones | RHONE-POULENC S.A. (FR) | 1977-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304447-A1 | A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES | ARSA, TPST2, STS | CA1 3612/4885CA2 1552/4885CA12 2293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.