SCHEMBL3694658

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3694655	1.00	L3MBTL1 (0.34)	L3MBTL1THRBNPSR1ALOX5SMN1; SMN2
	SCHEMBL16693386	0.92	L3MBTL1 (0.40)	L3MBTL1THRBALOX5SMN1; SMN2APP
	SCHEMBL16693328	0.88	SIRT5 (0.41)	THRBNPSR1SMN1; SMN2ALDH1A1CYP3A4
	SCHEMBL3196968	0.87	PPARA (0.34)	L3MBTL1NPSR1SMN1; SMN2ALDH1A1CYP3A4
	SCHEMBL1803270	0.87	PPARA (0.34)	L3MBTL1NPSR1SMN1; SMN2ALDH1A1CYP3A4
	SCHEMBL16693225	0.83	THRB (0.39)	L3MBTL1THRBALDH1A1CYP3A4HPGD
	SCHEMBL8855913	0.83	ALDH1A1 (0.39)	L3MBTL1NPSR1ALDH1A1CYP3A4HPGD
	SCHEMBL7174796	0.83	ALDH1A1 (0.39)	L3MBTL1NPSR1ALDH1A1CYP3A4HPGD
	SCHEMBL16693281	0.82	MAPT (0.47)	L3MBTL1NPSR1ALOX5ALDH1A1CYP3A4
	SCHEMBL3258581	0.82	CHRNB2 (0.34)	NPSR1SMN1; SMN2ALDH1A1HPGDPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.