Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 12/20 | 0.55 |
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
| ▸ | MPO | P05164 | 3/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5241306 | 0.83 | ADRB2 (0.54) | ICMTHTR6MPO | |
| SCHEMBL5239371 | 0.79 | ADRB2 (0.52) | ICMTHTR6MPO | |
| SCHEMBL15792328 | 0.77 | ICMT (0.49) | ICMTHTR6KDM4CCNR1CNR2 | |
| SCHEMBL7734107 | 0.76 | ICMT (0.50) | ICMTHTR6MPO | |
| SCHEMBL15536096 | 0.75 | CNR2 (0.53) | ICMTCNR1CNR2 | |
| SCHEMBL8233006 | 0.75 | HTR6 (0.48) | ICMTHTR6 | |
| SCHEMBL12874879 | 0.75 | HTR1A (0.51) | ICMTHTR6 | |
| SCHEMBL5923660 | 0.74 | ADRB2 (0.64) | ICMTHTR6MPO | |
| Cadaverine Tartrate SCHEMBL3703327 | 0.73 | LMNA (0.45) | ICMTMPO | |
| Hydrochloric Acid SCHEMBL16592500 | 0.73 | ADRB2 (0.62) | ICMTHTR6MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120122948-A1 | 3-ALKYL-5-FLUOROINDOLE DERIVATIVES AS MYELOPEROXIDASE INHIBITORS | UNIVERSITE LIBRE DE BEUXELLES (BE) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122948-A1 | 3-ALKYL-5-FLUOROINDOLE DERIVATIVES AS MYELOPEROXIDASE INHIBITORS | MPO, SERPINB1, MAOA | ICMT 2029/4885HTR6 228/4885MPO 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.