Diatrizoic Acid

Diatrizoic Acid

SCHEMBL37116

CC(=O)Nc1c(I)c(NC(C)=O)c(I)c(C(=O)[O-])c1I.[Na+]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Diatrizoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA1 known ✓ P00915 2/20 0.31
CA2 known ✓ P00918 1/20 0.30
LMNA P02545 4/20 1.00
SMN1; SMN2 Q16637 1/20 0.42
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diatrizoic Acid SCHEMBL6286191 1.00 LMNA (1.00) LMNASMN1; SMN2MEN1KMT2ACA1
Diatrizoic Acid SCHEMBL3076099 0.98 LMNA (0.96) LMNASMN1; SMN2MEN1KMT2A
Diatrizoic Acid SCHEMBL19379574 0.98 LMNA (0.96) LMNASMN1; SMN2MEN1KMT2A
Diatrizoic Acid SCHEMBL3338333 0.98 LMNA (0.96) LMNASMN1; SMN2MEN1KMT2A
SCHEMBL8815549 0.96 LMNA (0.92) LMNASMN1; SMN2MEN1KMT2ACA1
Diatrizoic Acid SCHEMBL7198501 0.96 LMNA (0.92) LMNASMN1; SMN2MEN1KMT2ACA1
Diatrizoic Acid SCHEMBL21243193 0.93 LMNA (0.86) LMNASMN1; SMN2MEN1KMT2A
Iothalamic Acid SCHEMBL159919 0.86 LMNA (0.75) LMNASMN1; SMN2
Iothalamic Acid SCHEMBL30496108 0.86 LMNA (0.75) LMNASMN1; SMN2
Metrizoic Acid SCHEMBL11334827 0.84 LMNA (0.71) LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 16047 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4692793-A1 BLOOD COLLECTION CONTAINER, AND METHOD FOR SEPARATING MONONUCLEAR CELLS Sekisui Medical Co., Ltd. (JP) 2026-02-11 EP claimed
US-20260028586-A1 METHODS FOR PRODUCING CELL POPULATIONS WITH INCREASED NUCLEIC ACID UPTAKE ZEON CORPORATION (JP) 2026-01-29 US claimed
US-12493029-B2 Compositions, methods, and kits for the isolation of extracellular vesicles EXOSOME DIAGNOSTICS, INC. (US) 2025-12-09 US claimed
WO-2025202247-A1 A METHOD OF SEPARATING TARGET CELLS FROM NON-TARGET CELLS IN A LIQUID BIOPSY SAMPLE, AND A KIT THEREFOR OSAID MOHAMMAD (SE) 2025-10-02 WO claimed
WO-2025124483-A1 ORAL DRUG DOSAGE FORM FOR TARGETED DRUG DELIVERY BASED ON TRACKING MARKER AND METHODS OF DESIGN AND USE THEREOF Triastek, Inc. (CN) 2025-06-19 WO claimed
WO-2025121491-A1 METHOD FOR PRODUCING TONSIL-DERIVED MESENCHYMAL STEM CELLS 연세대학교 원주산학협력단 2025-06-12 WO claimed
WO-2025107704-A1 NEW-TYPE ANTIFOULING DEVELOPING COATING MATERIAL, AND PREPARATION METHOD THEREFOR AND USE THEREOF 苏州银炙新材料科技有限公司 2025-05-30 WO claimed
US-20250154554-A1 ANTIMICROBIAL SUSCEPTIBILITY FASTINOV, SA (PT) 2025-05-15 US claimed
EP-4543498-A2 COMPOSITION AND METHOD FOR DIAGNOSTIC IMAGING Suntec Medical, Inc. (US) 2025-04-30 EP claimed
CN-119897141-A Porous rod-like carbon nitride photocatalytic material and preparation method and application thereof 东南大学 2025-04-29 CN claimed
US-5415546-A Markers COX SR RONALD W (US) 1995-05-16 US claimed
WO-1994021190-A1 RADIOPAQUE DENTAL COMPOSITE AND MATERIALS COX RONALD W (US) 1994-09-29 WO claimed
US-5260186-A Isolation of lymphocytes, centrifuging CERCEK BORIS (US) 1993-11-09 US claimed
US-5149712-A Treatment of corneal edema with diatrizoate solutions SCHACHAR RONALD A (US) 1992-09-22 US claimed
EP-0439548-A1 PROVISION OF DENSITY SPECIFIC BLOOD CELLS FOR THE STRUCTUREDNESS OF THE CYTOPLASMIC MARIX (SCM) TEST. CERCEK BORIS (US) 1991-08-07 EP claimed
WO-1990004785-A1 PROVISION OF DENSITY SPECIFIC BLOOD CELLS FOR THE STRUCTUREDNESS OF THE CYTOPLASMIC MATRIX (SCM) TEST CERCEK BORIS (US) 1990-05-03 WO claimed
US-4735795-A Alkylammonium complexes of diatrizoic acid as X-ray contrast agents E. R. SQUIBB & SONS, INC. (US) 1988-04-05 US claimed
EP-0028842-A2 Improved medium for the separation of human blood leucocytes Ferrante, Antonio (AU) 1981-05-20 EP claimed
US-4255256-A HIGH MOLECULAR WEIGHT SUCROSE OR GLUCOSE POLYMER AND A WATER SOLUBLE METRIZOATE OR DIATRIZOATE COMPOUND FERRANTE ANTONIO 1981-03-10 US claimed
US-4192859-A MEDICAL DIAGNOSIS USING X-RAYS E. R. SQUIBB & SONS, INC. (US) 1980-03-11 US claimed