Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 4/20 | 0.43 |
| ▸ | DBF4 | Q9UBU7 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | IRS1 | P35568 | 1/20 | 0.40 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | OGA | O60502 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30839468 | 0.83 | LMNA (0.63) | LMNAP2RY1HPGDKDM4EALDH1A1 | |
| SCHEMBL3717062 | 0.83 | LMNA (0.63) | LMNAP2RY1HPGDKDM4EALDH1A1 | |
| SCHEMBL22617519 | 0.82 | P2RY1 (0.44) | LMNAP2RY1CDC7DBF4KDM4E | |
| SCHEMBL22617535 | 0.80 | P2RY1 (0.43) | LMNAP2RY1CDC7DBF4HPGD | |
| SCHEMBL2179717 | 0.79 | TRPM8 (0.58) | LMNACDC7DBF4HPGDKDM4E | |
| SCHEMBL17212202 | 0.78 | CDC7 (0.62) | CDC7DBF4HPGDKDM4EALDH1A1 | |
| SCHEMBL22617530 | 0.77 | CDC7 (0.63) | LMNACDC7DBF4HPGDKDM4E | |
| SCHEMBL12571310 | 0.77 | TERT (0.43) | LMNAP2RY1KDM4EALDH1A1TERT | |
| SCHEMBL22619842 | 0.76 | CDC7 (0.47) | LMNAP2RY1CDC7DBF4AKT1 | |
| SCHEMBL1638585 | 0.76 | CDC7 (0.56) | CDC7DBF4KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3388428-B1 | FIVE-MEMBERED HETEROCYCLIC AMIDES WNT PATHWAY INHIBITOR | SUZHOU SINOVENT PHARMACEUTICALS COMPANY (CN) | 2021-08-04 | — | — | EP | disclosed |
| US-10821104-B2 | Five-membered heterocyclic amides WNT pathway inhibitor | Suzhou Sinovent Pharmaceuticals Co., Ltd. (CN) | 2020-11-03 | — | — | US | disclosed |
| EP-3216798-A2 | KETOLIDE COMPOUNDS | Wockhardt Limited (IN) | 2017-09-13 | — | — | EP | disclosed |
| EP-2673285-B1 | KETOLIDE COMPOUNDS | WOCKHARDT LTD (IN) | 2017-07-19 | — | — | EP | disclosed |
| US-20160083412-A1 | KETOLIDE COMPOUNDS | WOCKHARDT LIMITED (IN) | 2016-03-24 | — | — | US | disclosed |
| US-20160083412-A1 | KETOLIDE COMPOUNDS | WOCKHARDT LIMITED (IN) | 2016-03-24 | — | — | US | disclosed |
| US-9175031-B2 | Ketolide compounds | WOCKHARDT LIMITED (IN) | 2015-11-03 | — | — | US | disclosed |
| US-9175031-B2 | Ketolide compounds | WOCKHARDT LIMITED (IN) | 2015-11-03 | — | — | US | disclosed |
| EP-2435460-B1 | KETOLIDE COMPOUNDS HAVING ANTIMICROBIAL ACTIVITY | WOCKHARDT LTD (IN) | 2015-01-07 | — | — | EP | disclosed |
| CN-102459296-B | ketolide compounds having antimicrobial activity | WOCKHARDT RESEARCH CENTRE (IN) | 2014-10-29 | — | — | CN | disclosed |
| US-8541420-B2 | Ketolide compounds having antimicrobial activity | WOCKHARDT LTD. (IN) | 2013-09-24 | — | — | US | disclosed |
| WO-2012076989-A1 | KETOLIDE COMPOUNDS | WOCKHARDT LIMITED (IN) | 2012-06-14 | — | — | WO | disclosed |
| US-20120142710-A1 | Ketolide Compounds Having Antimicrobial Activity | WOCKHARDT LIMITED (IN) | 2012-06-07 | — | — | US | disclosed |
| WO-2010136971-A1 | KETOLIDE COMPOUNDS HAVING ANTIMICROBIAL ACTIVITY | WOCKHARDT RESEARCH CENTRE (IN) | 2010-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10821104-B2 | Five-membered heterocyclic amides WNT pathway inhibitor | WNT1, WNT3, WNT3A | LMNA 3903/4885P2RY1 3852/4885CDC7 258/4885 |
| US-20120142710-A1 | Ketolide Compounds Having Antimicrobial Activity | CYP51A1, AKR1A1, AKR1C1 | LMNA 3964/4885P2RY1 3123/4885CDC7 2069/4885 |
| US-20160083412-A1 | KETOLIDE COMPOUNDS | AKR1C3, AKR1D1, AKR1C1 | LMNA 4283/4885P2RY1 800/4885CDC7 2205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.