SCHEMBL3733244

SCHEMBL3733244

CCN(CC)c1ccc(/C=C/C(C)=O)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.61
MAPT P10636 7/20 0.61
MEN1 O00255 5/20 0.61
KMT2A Q03164 5/20 0.61
POLB P06746 4/20 0.61
MAPK1 P28482 2/20 0.61
TDP1 Q9NUW8 2/20 0.61
RECQL P46063 2/20 0.61
TLR9 Q9NR96 2/20 0.61
L3MBTL1 Q9Y468 2/20 0.61
USP2 O75604 1/20 0.61
ALDH3A1 P30838 1/20 0.58
ALDH1A3 P47895 1/20 0.58
NPSR1 Q6W5P4 1/20 0.56
FGFR1 P11362 1/20 0.55
LMNA P02545 1/20 0.54
GLA P06280 2/20 0.53
CNR2 P34972 1/20 0.52
KDM4E B2RXH2 3/20 0.51
GAA P10253 3/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2027311 1.00 ALDH1A1 (0.61) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL2025372 0.88 ALDH1A1 (0.54) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL2025371 0.88 ALDH1A1 (0.54) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL10976207 0.87 FGFR1 (0.68) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL2913262 0.87 FGFR1 (0.68) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL2913259 0.87 FGFR1 (0.68) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL23866724 0.86 ALDH1A1 (0.61) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL4729449 0.86 ALDH1A1 (0.61) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL8313188 0.86 ALDH1A1 (0.61) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL11148174 0.84 ALDH1A1 (0.60) ALDH1A1MAPTMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1778176-B1 COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES HENKEL AG & CO KGAA (DE) 2012-07-25 EP claimed
US-7413579-B2 Method for dyeing fibers containing keratin HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-08-19 US claimed
EP-1780747-A2 A conductive electrode powder, a method for preparing the same, and uses thereof Samsung SDI Co., Ltd. (KR) 2007-05-02 EP claimed
EP-1534227-B1 AGENTS USED FOR DYEING KERATINOUS FIBERS HENKEL KGAA (DE) 2006-12-27 EP claimed
US-20060265818-A1 At least two oxidation dye precursors, at least one of which must be of the developer type or at least two oxo dye precursors, at least one of which must be a reactive carbonyl compound; hair dyes producing uniform and natural-looking, lightened color reflections HENKEL KOMMANDITGESELLSCHAFT AUF AKLLEN (HENKEL KGAA) (DE) 2006-11-30 US claimed
EP-1433469-B1 Composition for dyeing keratinous fibres HENKEL KGAA (DE) 2006-10-11 EP claimed
US-7105032-B2 Agents used for dyeing keratinous fibers HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2006-09-12 US claimed
US-20060084176-A1 Detection of uronium salts YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2006-04-20 US claimed
EP-1434557-B1 AGENT FOR THE COLORATION OF KERATIN-CONTAINING FIBERS HENKEL KGAA (DE) 2005-11-09 EP claimed
US-20050144740-A1 Agents used for dyeing keratinous fibers HENKEL AG & CO. KGAA (DE) 2005-07-07 US claimed
US-4367280-A AROMATIC CARBONYL COMPOUND AND P-DIALKYLAMINO AROMATIC CARBONYL COMPOUND COMBINATION POLYMERIZATION INITIATOR FUJI PHOTO FILM CO., LTD. (JP) 1983-01-04 US claimed
CN-113304129-B Application of mono-ketene monocarbonyl curcumin analogue in preparing antioxidant drugs 温州医科大学附属第二医院(温州医科大学附属育英儿童医院) 2022-11-08 CN disclosed
US-20100278767-A1 Lightening Agents and/or Dyes that Contain Aldehyde(s) HENKEL AG & CO. KGAA (DE) 2010-11-04 US disclosed
US-20090304620-A1 HAIR TREATMENT PRODUCTS COMPRISING POLYMERS HENKEL AG & CO. KGAA (DE) 2009-12-10 US disclosed
US-7413579-B2 Method for dyeing fibers containing keratin HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-08-19 US disclosed
EP-1780747-A2 A conductive electrode powder, a method for preparing the same, and uses thereof Samsung SDI Co., Ltd. (KR) 2007-05-02 EP disclosed
US-20060265818-A1 At least two oxidation dye precursors, at least one of which must be of the developer type or at least two oxo dye precursors, at least one of which must be a reactive carbonyl compound; hair dyes producing uniform and natural-looking, lightened color reflections HENKEL KOMMANDITGESELLSCHAFT AUF AKLLEN (HENKEL KGAA) (DE) 2006-11-30 US disclosed
US-20060084176-A1 Detection of uronium salts YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2006-04-20 US disclosed
US-4367280-A AROMATIC CARBONYL COMPOUND AND P-DIALKYLAMINO AROMATIC CARBONYL COMPOUND COMBINATION POLYMERIZATION INITIATOR FUJI PHOTO FILM CO., LTD. (JP) 1983-01-04 US disclosed
US-4290870-A 5-ISOXOLONE, AROMATIC CARBONYL, DIALKYLAMINO AROMATIC CARBONYL OR FUJI PHOTO FILM CO., LTD. (JP) 1981-09-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090304620-A1 HAIR TREATMENT PRODUCTS COMPRISING POLYMERS ASS1, SRM, COL1A1 ALDH1A1 27/4885MAPT 1499/4885MEN1 230/4885
US-20050144740-A1 Agents used for dyeing keratinous fibers KRT18, TUBB3, DSG1 ALDH1A1 343/4885MAPT 259/4885MEN1 4420/4885
US-20060265818-A1 At least two oxidation dye precursors, at least one of which must be of the developer type or at least two oxo dye precursors, at least one of which must be a reactive carbonyl compound; hair dyes producing uniform and natural-looking, lightened color reflections KRT18, CUTA, PLOD2 ALDH1A1 159/4885MAPT 821/4885MEN1 2481/4885
US-20100278767-A1 Lightening Agents and/or Dyes that Contain Aldehyde(s) CCR3, CBR3, CCRL2 ALDH1A1 105/4885MAPT 3855/4885MEN1 2901/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.