SCHEMBL381981

SCHEMBL381981

CC(C)=CCOCc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.54
ALDH1A1 P00352 1/20 0.47
ALOX5 P09917 1/20 0.45
CA1 P00915 3/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
KDM4E B2RXH2 1/20 0.42
POLB P06746 1/20 0.42
TRPV1 Q8NER1 1/20 0.41
IDO1 P14902 1/20 0.40
PPARG P37231 1/20 0.40
HTT P42858 1/20 0.40
MAOB P27338 1/20 0.40
AGXT P21549 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL795298 0.85 TRPV1 (0.60) ALDH1A1TRPV1
SCHEMBL795297 0.85 TRPV1 (0.60) ALDH1A1TRPV1
SCHEMBL22076597 0.85 TSHR (0.50) TSHRALDH1A1ALOX5CA1CA2
SCHEMBL21017017 0.85 TSHR (0.50) TSHRALDH1A1ALOX5CA1CA2
SCHEMBL12377556 0.84 TRPV1 (0.59) TRPV1
SCHEMBL11039509 0.84 TRPV1 (0.59) TRPV1
SCHEMBL11039511 0.84 TRPV1 (0.59) TRPV1
SCHEMBL25298017 0.83 FNTA (0.51) TSHRALDH1A1ALOX5CA1CA2
SCHEMBL25776221 0.83 FNTA (0.51) TSHRALDH1A1ALOX5CA1CA2
SCHEMBL20521373 0.82 ALDH1A1 (0.50) TSHRALDH1A1ALOX5MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250296906-A1 METHOD FOR PREPARING 4-HYDROXY-2-METHYLENE-BUTANAL, 4-HYDROXY-2-METHYL-BUT-2-ENAL AND ESTERS THEREOF BASF SE (DE) 2025-09-25 US disclosed
EP-4577517-A1 METHOD FOR PREPARING 4-HYDROXY-2-METHYLENE-BUTANAL, 4-HYDROXY-2-METHYL-BUT-2-ENAL AND ESTERS THEREOF BASF SE (DE) 2025-07-02 EP disclosed
EP-4577516-A1 METHOD FOR PREPARING 4-HYDROXY-2-METHYLENE-BUTANAL, 4-HYDROXY-2-METHYL-BUT-2-ENAL AND ESTERS THEREOF BASF SE (DE) 2025-07-02 EP disclosed
WO-2024042132-A1 METHOD FOR PREPARING 4-HYDROXY-2-METHYLENE-BUTANAL, 4-HYDROXY-2-METHYL-BUT-2-ENAL AND ESTERS THEREOF BASF SE (DE) 2024-02-29 WO disclosed
US-11479867-B2 Electrocatalytic alkene diazidation CORNELL UNIVERSITY (US) 2022-10-25 US disclosed
EP-1783111-B1 METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND SUMITOMO CHEMICAL CO (JP) 2015-04-08 EP disclosed
EP-2781522-A1 OPTICALLY ACTIVE BISOXAZOLINE COMPOUND, ASYMMETRIC CATALYST, AND METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANE COMPOUND USING SAID CATALYST Sumitomo Chemical Company, Limited (JP) 2014-09-24 EP disclosed
EP-2487149-A1 METHOD FOR PRODUCING KETONE JX Nippon Oil & Energy Corporation (JP) 2012-08-15 EP disclosed
US-20120197036-A1 METHOD FOR MANUFACTURING KETONE OSAKA UNIVERSITY (JP) 2012-08-02 US disclosed
CN-102548942-A Method for producing ketone JX NIPPON OIL & ENERGY CORP 2012-07-04 CN disclosed
US-20080027235-A1 Method for Producing Optically Active Cyclopropanecarboxylate Compound SUMITOMO CHEMICAL COMPANY, LIMITED 2008-01-31 US disclosed
US-20070112201-A1 Method for producing optically active cycloalkylidenebisoxazoline compound and intermediate thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-17 US disclosed
EP-1783111-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND Sumitomo Chemical Company, Limited (JP) 2007-05-09 EP disclosed
EP-1783130-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND Sumitomo Chemical Company, Limited (JP) 2007-05-09 EP disclosed
US-20070032659-A1 Process for producing optically active cyclopropane compound and asymmetric copper complex for use in the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-02-08 US disclosed
EP-1698617-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOALKYLIDENE BISOXAZOLINE COMPOUND AND INTERMEDIATE THEREOF Sumitomo Chemical Company, Limited (JP) 2006-09-06 EP disclosed
EP-1674445-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANE COMPOUND AND ASYMMETRIC COPPER COMPLEX FOR USE IN THE SAME Sumitomo Chemical Company, Limited (JP) 2006-06-28 EP disclosed
EP-0302406-B1 Novel alternate copolymers KURARAY CO (JP) 1994-10-05 EP disclosed
US-4814425-A ISOPENTENYL COMPOUNDS KURARAY CO., LTD. (JP) 1989-03-21 US disclosed
EP-0302406-A2 Novel alternate copolymers KURARAY CO., LTD. (JP) 1989-02-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250296906-A1 METHOD FOR PREPARING 4-HYDROXY-2-METHYLENE-BUTANAL, 4-HYDROXY-2-METHYL-BUT-2-ENAL AND ESTERS THEREOF ALDH1A2, ADH4, RBP4 TSHR 3564/4885ALDH1A1 21/4885ALOX5 16/4885
US-20070112201-A1 Method for producing optically active cycloalkylidenebisoxazoline compound and intermediate thereof CYP3A7, GRK7, CYP2A7 TSHR 2791/4885ALDH1A1 610/4885ALOX5 928/4885
US-20080027235-A1 Method for Producing Optically Active Cyclopropanecarboxylate Compound ACSL6, AOC1, CA6 TSHR 388/4885ALDH1A1 1222/4885ALOX5 184/4885
US-20120197036-A1 METHOD FOR MANUFACTURING KETONE CBR1, CBR3, DUOX1 TSHR 2444/4885ALDH1A1 79/4885ALOX5 1306/4885
US-20070032659-A1 Process for producing optically active cyclopropane compound and asymmetric copper complex for use in the same CBR3, AOC3, CBR1 TSHR 397/4885ALDH1A1 185/4885ALOX5 796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.