Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31125679 | 1.00 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B1PBRM1 | |
| SCHEMBL3987533 | 0.89 | MAOA (0.44) | KDM4EALDH1A1HSD17B1ACHEMAOA | |
| SCHEMBL1535917 | 0.79 | ACHE (0.56) | KDM4EALDH1A1HPGDHSD17B1PBRM1 | |
| SCHEMBL19950131 | 0.76 | HSD17B1 (0.47) | KDM4EALDH1A1HPGDHSD17B1PBRM1 | |
| SCHEMBL11663902 | 0.76 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B1MAOA | |
| SCHEMBL296542 | 0.76 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B1CASP1 | |
| SCHEMBL30070327 | 0.76 | HSD17B1 (0.47) | KDM4EALDH1A1HPGDHSD17B1PBRM1 | |
| SCHEMBL386061 | 0.76 | SLC22A8 (0.49) | KDM4EALDH1A1HPGDHSD17B1PBRM1 | |
| SCHEMBL15287071 | 0.76 | CASP1 (0.41) | KDM4EALDH1A1HPGDHSD17B1MCL1 | |
| SCHEMBL29660467 | 0.76 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11731961-B2 | Phenyl propionic acid derivatives and uses thereof | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2023-08-22 | — | — | US | disclosed |
| US-11731961-B2 | Phenyl propionic acid derivatives and uses thereof | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2023-08-22 | — | — | US | disclosed |
| US-11731961-B2 | Phenyl propionic acid derivatives and uses thereof | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2023-08-22 | — | — | US | disclosed |
| EP-3555076-B1 | NOVEL PHENYL PROPIONIC ACID DERIVATIVES AND USES THEREOF | IL DONG PHARMA (KR) | 2023-04-05 | — | — | EP | disclosed |
| CN-110049984-B | Phenylpropionic acid derivatives and use thereof | 日东制药株式会社 | 2022-11-15 | — | — | CN | disclosed |
| US-20220112185-A1 | NOVEL PHENYL PROPIONIC ACID DERIVATIVES AND USES THEREOF | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-04-14 | — | — | US | disclosed |
| US-20220064154-A1 | NOVEL PHENYL PROPIONIC ACID DERIVATIVES AND USES THEREOF | ILDONG PHARMACEUTICAL CO, LTD. (KR) | 2022-03-03 | — | — | US | disclosed |
| US-11225472-B2 | Phenyl propionic acid derivatives and uses thereof | IL DONG PHARMACEUTICAL CO., LTD. | 2022-01-18 | — | — | US | disclosed |
| CN-113072551-A | Nitrogen-containing biphenyl derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2021-07-06 | — | — | CN | disclosed |
| US-20200223833-A1 | NOVEL PHENYL PROPIONIC ACID DERIVATIVES AND USES THEREOF | IL DONG PHARMACEUTICAL CO., LTD. (KR) | 2020-07-16 | — | — | US | disclosed |
| US-20130289074-A1 | NEW INDANYLOXYDIHYDROBENZOFURANYLACETIC ACIDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-10-31 | — | — | US | disclosed |
| US-20130289074-A1 | NEW INDANYLOXYDIHYDROBENZOFURANYLACETIC ACIDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-10-31 | — | — | US | disclosed |
| US-20130289074-A1 | NEW INDANYLOXYDIHYDROBENZOFURANYLACETIC ACIDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-10-31 | — | — | US | disclosed |
| WO-2013144098-A1 | NEW INDANYLOXYDIHYDROBENZOFURANYLACETIC ACID DERIVATIVES AND THEIR USE AS GPR40 RECEPTOR AGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-10-03 | — | — | WO | disclosed |
| WO-2013144098-A1 | NEW INDANYLOXYDIHYDROBENZOFURANYLACETIC ACID DERIVATIVES AND THEIR USE AS GPR40 RECEPTOR AGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-10-03 | — | — | WO | disclosed |
| US-7485655-B2 | 2-Aminothiazole allosteric enhancers of A1 adenosine receptors | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2009-02-03 | — | — | US | disclosed |
| EP-1583530-A4 | 2-AMINOTHIAZOLE ALLOSTERIC ENHANCERS OF A1-ADENOSINE RECEPTORS | UNIV VIRGINIA (US) | 2008-07-23 | — | — | EP | disclosed |
| EP-1583530-A1 | 2-AMINOTHIAZOLE ALLOSTERIC ENHANCERS OF A1-ADENOSINE RECEPTORS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2005-10-12 | — | — | EP | disclosed |
| US-20050027125-A1 | 2-Aminothiazole allosteric enhancers of a ?1? adenosine receptors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-02-03 | — | — | US | disclosed |
| WO-2003061655-A1 | 2-AMINOTHIAZOLE ALLOSTERIC ENHANCERS OF A1 ADENOSINE RECEPTORS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2003-07-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220064154-A1 | NOVEL PHENYL PROPIONIC ACID DERIVATIVES AND USES THEREOF | GPR119, GPR65, GPR55 | KDM4E 3484/4885ALDH1A1 872/4885HPGD 2338/4885 |
| US-11225472-B2 | Phenyl propionic acid derivatives and uses thereof | GPR119, GPR55, GPR65 | KDM4E 3561/4885ALDH1A1 755/4885HPGD 1872/4885 |
| US-20050027125-A1 | 2-Aminothiazole allosteric enhancers of a ?1? adenosine receptors | ADORA1, ADORA2A, ADORA2B | KDM4E 2302/4885ALDH1A1 512/4885HPGD 2608/4885 |
| US-20220112185-A1 | NOVEL PHENYL PROPIONIC ACID DERIVATIVES AND USES THEREOF | GPR119, GPR55, GPR65 | KDM4E 3215/4885ALDH1A1 698/4885HPGD 2362/4885 |
| US-20200223833-A1 | NOVEL PHENYL PROPIONIC ACID DERIVATIVES AND USES THEREOF | GPR119, GLP1R, GPR65 | KDM4E 3459/4885ALDH1A1 806/4885HPGD 2097/4885 |
| US-20130289074-A1 | NEW INDANYLOXYDIHYDROBENZOFURANYLACETIC ACIDS | GPR119, GPR55, GPR52 | KDM4E 3506/4885ALDH1A1 216/4885HPGD 1821/4885 |
| US-11731961-B2 | Phenyl propionic acid derivatives and uses thereof | GPR119, GPR65, GPR55 | KDM4E 3730/4885ALDH1A1 731/4885HPGD 2009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.