Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 1/20 | 0.54 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3497625 | 0.88 | TDP1 (0.49) | GRM8GRM4TDP1CYP1A2ALDH1A1 | |
| SCHEMBL20211524 | 0.85 | GRM8 (0.52) | GRM8GRM4TDP1CYP1A2ALDH1A1 | |
| SCHEMBL29478417 | 0.84 | GRM8 (0.56) | GRM8GRM4TDP1CYP1A2ALDH1A1 | |
| SCHEMBL5898971 | 0.83 | GRM8 (0.46) | GRM8GRM4TDP1CYP1A2ALDH1A1 | |
| SCHEMBL9398085 | 0.82 | TDP1 (0.56) | GRM8GRM4TDP1CYP1A2ALDH1A1 | |
| SCHEMBL2026857 | 0.81 | ALDH1A1 (0.53) | GRM8GRM4TDP1CYP1A2ALDH1A1 | |
| SCHEMBL2026853 | 0.81 | ALDH1A1 (0.53) | GRM8GRM4TDP1CYP1A2ALDH1A1 | |
| SCHEMBL7213380 | 0.80 | GRM8 (0.42) | GRM8GRM4TDP1CYP1A2ALDH1A1 | |
| SCHEMBL10662852 | 0.79 | GRM8 (0.52) | GRM8GRM4TDP1CYP1A2ALDH1A1 | |
| SCHEMBL2130850 | 0.78 | ALDH1A1 (0.50) | GRM8GRM4TDP1CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114878550-B | Multifunctional health monitoring contact lens and preparation and detection methods thereof | 温州医科大学 | 2026-05-12 | — | — | CN | disclosed |
| CN-114878550-A | Multifunctional health monitoring contact lens and preparation and detection method thereof | 温州医科大学 | 2022-08-09 | — | — | CN | disclosed |
| US-20150293106-A1 | DIAROMATIC AMINO ACID SUBSTRATE FOR CATHEPSIN DETECTION | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2015-10-15 | — | — | US | disclosed |
| EP-1450777-B1 | PHARMACEUTICAL COMPOSITION CONTAINING CHALCONE OR ITS DERIVATIVES FOR MATRIX METALLOPROTEINASE INHIBITORY ACTIVITY | ANGIOLAB INC (KR) | 2013-05-08 | — | — | EP | disclosed |
| US-7572831-B2 | Composition containing chalcone | ANGIOLAB, INC. (KR) | 2009-08-11 | — | — | US | disclosed |
| EP-1504094-A2 | PEPTIDE COMPOUNDS AND THEIR USE AS PROTEASE SUBSTRATES | Pharmacia Corporation (US) | 2005-02-09 | — | — | EP | disclosed |
| WO-2004100986-A2 | PHARMACEUTICAL USE OF AN ADAM 10 INHIBITORY SUBSTANCE | CELLTECH R & D LIMITED (GB) | 2004-11-25 | — | — | WO | disclosed |
| US-20040209952-A1 | Composition containing chalcone | ANGIOLAB, INC. (KR) | 2004-10-21 | — | — | US | disclosed |
| EP-1450777-A1 | PHARMACEUTICAL COMPOSITION CONTAINING CHALCONE OR ITS DERIVATIVES FOR MATRIX METALLOPROTEINASE INHIBITORY ACTIVITY | Angiolab Inc. (KR) | 2004-09-01 | — | — | EP | disclosed |
| US-20040018561-A1 | Peptide compounds and their use as protease substrates | PHARMACIA CORPORATION | 2004-01-29 | — | — | US | disclosed |
| WO-2003095475-A2 | PEPTIDE COMPOUNDS AND THEIR USE AS PROTEASE SUBSTRATES | PHARMACIA CORPORATION (US) | 2003-11-20 | — | — | WO | disclosed |
| WO-2003037315-A1 | PHARMACEUTICAL COMPOSITION CONTAINING CHALCONE OR ITS DERIVATIVES FOR MATRIX METALLOPROTEINASE INHIBITORY ACTIVITY | ANGIOLAB INC. (KR) | 2003-05-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150293106-A1 | DIAROMATIC AMINO ACID SUBSTRATE FOR CATHEPSIN DETECTION | CTSV, CTSZ, CTSH | GRM8 4052/4885GRM4 4398/4885TDP1 2260/4885 |
| US-20040018561-A1 | Peptide compounds and their use as protease substrates | MMP3, MMP25, MMP11 | GRM8 4283/4885GRM4 3832/4885TDP1 1806/4885 |
| US-20040209952-A1 | Composition containing chalcone | MMP25, MMP13, MMP17 | GRM8 4197/4885GRM4 4446/4885TDP1 2570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.