SCHEMBL4046799 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	ALDH1A1	P00352	1/20	0.39

▸	CTSK	P43235	16/20	0.39

▸	CTSL	P07711	16/20	0.39

▸	CTSS	P25774	12/20	0.39

▸	CTSB	P07858	4/20	0.39

▸	CTSV	O60911	2/20	0.39

▸	ELOVL6	Q9H5J4	1/20	0.36

▸	PREP	P48147	1/20	0.36

▸	FAP	Q12884	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4044230	0.94	CTSL (0.40)	CTSKCTSLCTSSCTSBCTSV
SCHEMBL4050010	0.92	CTSK (0.44)	ALDH1A1CTSKCTSLCTSSCTSB
SCHEMBL4039771	0.90	ALDH1A1 (0.38)	ALDH1A1CTSKCTSLCTSSCTSB
SCHEMBL4043678	0.90	ALDH1A1 (0.38)	ALDH1A1CTSKCTSLCTSSCTSB
SCHEMBL4046989	0.89	ALDH1A1 (0.38)	ALDH1A1ELOVL6PREPFAP
SCHEMBL4042234	0.89	ELOVL6 (0.39)	CTSKCTSLCTSSCTSBCTSV
SCHEMBL4048186	0.88	ALDH1A1 (0.36)	ALDH1A1CTSKPREPFAP
SCHEMBL4043292	0.88	ALDH1A1 (0.37)	ALDH1A1CTSKPREPFAP
SCHEMBL4051941	0.87	ELOVL6 (0.38)	CTSKCTSLCTSSCTSBCTSV
SCHEMBL4047431	0.86	ALDH1A1 (0.37)	ALDH1A1PREPFAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1546150-B1	PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES	AMURA THERAPEUTICS LTD (GB)	2009-03-04	—	—	EP	claimed