Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4045552 | 0.94 | ITGB3 (0.37) | CTSKP2RX7 | |
| SCHEMBL4047305 | 0.94 | P2RX7 (0.37) | CTSKP2RX7 | |
| SCHEMBL4047214 | 0.93 | CTSK (0.33) | CTSKP2RX7OPRM1 | |
| SCHEMBL4046036 | 0.90 | P2RX7 (0.36) | CTSKP2RX7ACE | |
| SCHEMBL6234334 | 0.90 | CTSK (0.44) | CTSKACEACE2 | |
| SCHEMBL4047763 | 0.89 | CTSK (0.44) | CTSK | |
| SCHEMBL4041133 | 0.88 | CTSK (0.36) | CTSK | |
| SCHEMBL4045610 | 0.88 | POLB (0.33) | CTSKACEACE2OPRM1 | |
| SCHEMBL4041003 | 0.84 | CTSL (0.39) | CTSK | |
| SCHEMBL4042222 | 0.84 | CNR1 (0.34) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |