Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 7/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.36 |
| ▸ | ITGB7 | P26010 | 4/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 3/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4041712 | 0.94 | ITGA4 (0.40) | ITGA4ITGB7BCL2CTSKITGB1 | |
| SCHEMBL4041901 | 0.94 | P2RX7 (0.39) | P2RX7ITGA4ITGB7CTSKITGB1 | |
| SCHEMBL4043833 | 0.92 | F10 (0.36) | P2RX7ITGA4ITGB7CTSKITGB1 | |
| SCHEMBL4047239 | 0.90 | CTSK (0.34) | P2RX7CTSKACE | |
| SCHEMBL4046868 | 0.89 | ITGB1 (0.37) | P2RX7ITGA4ITGB7BCL2CTSK | |
| SCHEMBL4045912 | 0.88 | ITGA4 (0.34) | P2RX7ITGA4ITGB7CTSKITGB1 | |
| SCHEMBL4044695 | 0.88 | CTSK (0.36) | CTSK | |
| SCHEMBL4041003 | 0.86 | CTSL (0.39) | CTSK | |
| SCHEMBL4045552 | 0.84 | ITGB3 (0.37) | P2RX7ITGA4ITGB7BCL2CTSK | |
| SCHEMBL4047305 | 0.84 | P2RX7 (0.37) | P2RX7ITGA4ITGB7CTSKITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2016064-A2 | METHODS FOR THE PREPARATION OF PYRAZOLE-CONTAINING COMPOUNDS | Janssen Pharmaceutica, N.V. (BE) | 2009-01-21 | — | — | EP | claimed |
| WO-2007131153-A2 | METHODS FOR THE PREPARATION OF PYRAZOLE-CONTAINING COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-11-15 | — | — | WO | claimed |