Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | F12 | P00748 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4042222 | 0.91 | CNR1 (0.34) | CTSKCTSLCTSS | |
| SCHEMBL4045912 | 0.90 | ITGA4 (0.34) | POLBCTSKCTSLCTSBCTSS | |
| SCHEMBL6211991 | 0.90 | CTSL (0.40) | CTSKCTSLCTSBCTSSACE | |
| SCHEMBL4047239 | 0.88 | CTSK (0.34) | CTSKACEACE2OPRM1 | |
| SCHEMBL4044768 | 0.85 | CTSL (0.44) | CTSKCTSLCTSBCTSS | |
| SCHEMBL4041433 | 0.84 | ALDH1A1 (0.35) | POLBCTSLCTSBCTSSF12 | |
| SCHEMBL6234334 | 0.83 | CTSK (0.44) | CTSKCTSLCTSSACEACE2 | |
| SCHEMBL4047305 | 0.83 | P2RX7 (0.37) | CTSK | |
| SCHEMBL4044603 | 0.82 | MC4R (0.37) | POLBCTSKCTSLCTSBCTSS | |
| SCHEMBL4045047 | 0.82 | CTSL (0.37) | POLBCTSKCTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |