Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 4/20 | 0.37 |
| ▸ | CTSK | P43235 | 3/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 4/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.34 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | PTGFR | P43088 | 1/20 | 0.32 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | YAP1 | P46937 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4047239 | 0.94 | CTSK (0.34) | P2RX7CTSK | |
| SCHEMBL4045552 | 0.93 | ITGB3 (0.37) | P2RX7CTSKITGA4ITGB7ITGB1 | |
| SCHEMBL4041901 | 0.90 | P2RX7 (0.39) | P2RX7CTSKITGA4ITGB7ITGB1 | |
| SCHEMBL4047214 | 0.89 | CTSK (0.33) | P2RX7CTSKITGA4ITGB1 | |
| SCHEMBL4047763 | 0.88 | CTSK (0.44) | CTSK | |
| SCHEMBL4041133 | 0.87 | CTSK (0.36) | CTSK | |
| SCHEMBL4046036 | 0.84 | P2RX7 (0.36) | P2RX7CTSKITGA4ITGB7ITGB1 | |
| SCHEMBL6234334 | 0.84 | CTSK (0.44) | CTSKITGA4ITGB1 | |
| SCHEMBL4041436 | 0.84 | ALDH1A1 (0.39) | P2RX7ITGA4ITGB7ITGB1 | |
| SCHEMBL4041712 | 0.83 | ITGA4 (0.40) | CTSKITGA4ITGB7ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |