SCHEMBL4135007

SCHEMBL4135007

CN(Cc1cc(-c2cccnc2F)c(S(=O)(=O)c2nccn2C)s1)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
C1S P09871 1/20 0.33
LIPG Q9Y5X9 3/20 0.33
KAT5 Q92993 1/20 0.32
KAT8 Q9H7Z6 1/20 0.32
RAB9A P51151 1/20 0.32
MCL1 Q07820 1/20 0.32
KCNA5 P22460 1/20 0.31
LIPC P11150 1/20 0.31
KDM4E B2RXH2 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4125901 0.84 NAMPT (0.35) LIPGLIPC
SCHEMBL4135014 0.84 ADAM17 (0.35) C1SLIPGKAT5KAT8MCL1
SCHEMBL4127364 0.83 MAOA (0.36) C1SLIPGLIPCKDM4E
SCHEMBL4117657 0.83 GPBAR1 (0.33) LIPGLIPC
Hydrochloric Acid SCHEMBL3697191 0.82 CYP2A6 (0.37) C1SLIPGKAT5KAT8MCL1
SCHEMBL3782033 0.81 NAMPT (0.37)
SCHEMBL3649326 0.81 HTR6 (0.39)
SCHEMBL4125599 0.81 LIPG (0.33) LIPGLIPC
SCHEMBL4125938 0.80 FFAR4 (0.34) LIPGLIPC
SCHEMBL4136581 0.80 CTSD (0.33) LIPGLIPC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2190822-B1 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS TAKEDA PHARMACEUTICAL (JP) 2014-12-31 EP disclosed
US-20090156642-A1 5-Membered heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090156642-A1 5-Membered heterocyclic compound CEL, PGA5, COG5 C1S 1997/4885LIPG 2467/4885KAT5 1522/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.