SCHEMBL420161

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL420631	0.90	SERPINE1 (0.82)	SERPINE1CNR1CNR2MAP4K4CSNK1G2
	SCHEMBL420162	0.89	SERPINE1 (0.80)	SERPINE1CNR1CNR2MAP4K4CSNK1G2
	SCHEMBL418848	0.88	SERPINE1 (0.79)	SERPINE1PPARGPPARASUCNR1AKR1C4
	SCHEMBL419421	0.87	SERPINE1 (0.78)	SERPINE1CNR1CNR2MAP4K4CSNK1G2
	SCHEMBL418263	0.80	SERPINE1 (1.00)	SERPINE1PPARGPPARAMMP9SUCNR1
	SCHEMBL416775	0.80	SERPINE1 (0.71)	SERPINE1CNR1PPARGPPARASUCNR1
	SCHEMBL420754	0.79	SERPINE1 (1.00)	SERPINE1PPARGPPARAAKR1C4AKR1C3
	SCHEMBL29896767	0.79	SERPINE1 (1.00)	SERPINE1PPARGPPARAAKR1C4AKR1C3
	SCHEMBL420345	0.78	SERPINE1 (0.69)	SERPINE1SUCNR1AKR1C4AKR1C3AKR1C2
	SCHEMBL421056	0.78	SERPINE1 (1.00)	SERPINE1PPARGPPARASUCNR1AKR1C4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.