SCHEMBL420754

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29896767	1.00	SERPINE1 (1.00)	SERPINE1PPARGL3MBTL1MEN1KMT2A
	SCHEMBL417230	0.91	SERPINE1 (0.83)	SERPINE1PPARGL3MBTL1MEN1KMT2A
	SCHEMBL422042	0.90	SERPINE1 (0.81)	SERPINE1PPARGL3MBTL1MEN1KMT2A
	SCHEMBL29838623	0.90	SERPINE1 (0.81)	SERPINE1PPARGL3MBTL1MEN1KMT2A
	SCHEMBL420755	0.89	SERPINE1 (0.80)	SERPINE1PPARGL3MBTL1MEN1KMT2A
	SCHEMBL418419	0.87	SERPINE1 (0.77)	SERPINE1PPARGL3MBTL1MEN1KMT2A
	SCHEMBL418848	0.85	SERPINE1 (0.79)	SERPINE1PPARGL3MBTL1MEN1KMT2A
	SCHEMBL419786	0.83	SERPINE1 (0.71)	SERPINE1PPARGL3MBTL1MEN1KMT2A
	SCHEMBL421056	0.82	SERPINE1 (1.00)	SERPINE1PPARGPPARAAKR1C4AKR1C3
	SCHEMBL418645	0.82	SERPINE1 (0.69)	SERPINE1PPARGL3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.