SCHEMBL4222097

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9158501	0.86	MTNR1A (0.55)	CYP2C9AKR1C3MTNR1AMTNR1BCYP1A2
	SCHEMBL2271588	0.84	SERPINE1 (0.64)	POLBNR1H4SERPINE1HPSEMEN1
	SCHEMBL4216870	0.83	HPGD (0.54)	CYP2C9CYP2C19MTNR1AMTNR1BNR1H4
	SCHEMBL6361641	0.83	AKR1C3 (0.65)	AKR1C3AKR1C2MEN1KMT2A
	SCHEMBL13890889	0.82	MTNR1A (0.49)	CYP2C9CYP2C19MTNR1AMTNR1BCYP1A2
	SCHEMBL2269563	0.82	STK39 (0.57)	CYP2C9CYP2C19MAPK1GFERCYP1A2
	SCHEMBL2268019	0.82	MAPK1 (0.57)	CYP2C9CYP2C19POLBMAPK1GFER
	SCHEMBL11644513	0.82	HDAC2 (0.61)	MTNR1AMTNR1BEPHX1HPGDSMN1; SMN2
	SCHEMBL2272774	0.82	KMT2A (0.63)	POLBNR1H4SERPINE1HPSEMEN1
	SCHEMBL2273436	0.82	PYGM (0.70)	NR1H4SERPINE1HPSEMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.