Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GRN | P28799 | 1/20 | 0.34 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.34 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22337568 | 0.84 | SMN1; SMN2 (0.36) | SMN1; SMN2KMT2AMEN1KDM4EGLS | |
| SCHEMBL255124 | 0.82 | SMN1; SMN2 (0.39) | SMN1; SMN2KMT2AMEN1KDM4EGRN | |
| SCHEMBL20320404 | 0.82 | MEN1 (0.36) | SMN1; SMN2KMT2AMEN1KDM4EGLS | |
| SCHEMBL3436871 | 0.79 | PKM (0.45) | SMN1; SMN2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL20320349 | 0.79 | SMN1; SMN2 (0.33) | SMN1; SMN2KMT2AMEN1KDM4EGLS | |
| SCHEMBL20320344 | 0.79 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL20320338 | 0.79 | PDE2A (0.39) | SMN1; SMN2KMT2AMEN1CYP1A2PDE2A | |
| SCHEMBL20320345 | 0.79 | SMN1; SMN2 (0.33) | SMN1; SMN2KMT2AMEN1KDM4EGLS | |
| SCHEMBL20320342 | 0.77 | SMN1; SMN2 (0.33) | SMN1; SMN2GLS | |
| SCHEMBL20320341 | 0.77 | SMN1; SMN2 (0.33) | SMN1; SMN2KMT2AMEN1GLSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238296-A1 | METHODS OF REGULATING BCL11A EXPRESSION AND TREATMENT OF BCL11A-MEDIATED DISORDERS | FULCRUM THERAPEUTICS INC (US) | 2024-07-18 | — | — | US | disclosed |
| US-20240238296-A1 | METHODS OF REGULATING BCL11A EXPRESSION AND TREATMENT OF BCL11A-MEDIATED DISORDERS | FULCRUM THERAPEUTICS INC (US) | 2024-07-18 | — | — | US | disclosed |
| US-20240228484-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-07-11 | — | — | US | disclosed |
| US-12024500-B2 | Five-membered ring-substituted pyridazinol compounds and derivatives, preparation methods, herbicidal compositions and applications thereof | QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) | 2024-07-02 | — | — | US | disclosed |
| US-20240208902-A1 | CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-06-27 | — | — | US | disclosed |
| US-20240208902-A1 | CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-06-27 | — | — | US | disclosed |
| US-20240018162-A1 | BIFUNCTIONAL DEGRADERS OF HEMATOPOIETIC PROGENITOR KINASE AND THERAPEUTIC USES THEREOF | NURIX THERAPEUTICS, INC. | 2024-01-18 | — | — | US | disclosed |
| US-20230399337-A1 | NOVEL KINASE INHIBITORS EXHIBITING ANTI-CANCER ACTIVITY AND THEIR METHOD OF USE | ALLCRON PHARMA INC. | 2023-12-14 | — | — | US | disclosed |
| US-20230399337-A1 | NOVEL KINASE INHIBITORS EXHIBITING ANTI-CANCER ACTIVITY AND THEIR METHOD OF USE | ALLCRON PHARMA INC. | 2023-12-14 | — | — | US | disclosed |
| WO-2023217879-A1 | PYRROLIDIONE DERIVATIVES AS INHIBITORS OF NF KAPPA B INDUCING KINASE | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-16 | — | — | WO | disclosed |
| US-20070225167-A1 | 2-Ethyl-4,6-Dimethyl-Phenyl-Substituted Tetramic Acid Derivatives as Pest Control Agents and/or Herbicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-09-27 | — | — | US | disclosed |
| EP-1798230-A1 | Substituted alkylamine derivatives and methods of use | Amgen Inc. (US) | 2007-06-20 | — | — | EP | disclosed |
| US-20070129252-A1 | 2-Halo-6-alkylphenyl-substituted spirocyclic tetramic acid derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-06-07 | — | — | US | disclosed |
| US-20070093391-A1 | 4-Biphenyl-substituted pyrazolidin-3 5-diones pesticide agent and/or microbicide and/or herbicide | BAYER CROPSCIENCE AG (DE) | 2007-04-26 | — | — | US | disclosed |
| US-20070066488-A1 | Hetaryl-substituted pyrazolidindione derivatives with pesticidal characteristics | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-03-22 | — | — | US | disclosed |
| US-20070043045-A1 | Novel high affinity thiophene-based and furan-based kinase ligands | SCHERING CORPORATION | 2007-02-22 | — | — | US | disclosed |
| US-20070043045-A1 | Novel high affinity thiophene-based and furan-based kinase ligands | SCHERING CORPORATION | 2007-02-22 | — | — | US | disclosed |
| US-20070043057-A1 | Lonidamine analogs | THRESHOLD PHARMACEUTICALS, INC. (US) | 2007-02-22 | — | — | US | disclosed |
| US-20070015771-A1 | Lonidamine analogs | THRESHOLD PHARMACEUTICALS, INC. (US) | 2007-01-18 | — | — | US | disclosed |
| US-20070015664-A1 | 2,4,6-Phenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12024500-B2 | Five-membered ring-substituted pyridazinol compounds and derivatives, preparation methods, herbicidal compositions and applications thereof | DDT, CYP3A5, CYP4B1 | SMN1; SMN2 3696/4885KMT2A 1703/4885MEN1 4610/4885 |
| US-20070015664-A1 | 2,4,6-Phenyl substituted cyclic ketoenols | CYP4X1, KDM4E, KCNE1 | SMN1; SMN2 4514/4885KMT2A 321/4885MEN1 4847/4885 |
| US-20070066488-A1 | Hetaryl-substituted pyrazolidindione derivatives with pesticidal characteristics | DDT, CYP1A2, HPD | SMN1; SMN2 4638/4885KMT2A 2381/4885MEN1 4237/4885 |
| US-20070093391-A1 | 4-Biphenyl-substituted pyrazolidin-3 5-diones pesticide agent and/or microbicide and/or herbicide | DDT, CYP4X1, HPD | SMN1; SMN2 4748/4885KMT2A 1777/4885MEN1 4281/4885 |
| US-20240228484-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | MGLL, LPL, PNLIP | SMN1; SMN2 1579/4885KMT2A 1490/4885MEN1 2100/4885 |
| US-20240238296-A1 | METHODS OF REGULATING BCL11A EXPRESSION AND TREATMENT OF BCL11A-MEDIATED DISORDERS | BCLAF1, EED, BCL3 | SMN1; SMN2 1053/4885KMT2A 84/4885MEN1 3343/4885 |
| US-20070225167-A1 | 2-Ethyl-4,6-Dimethyl-Phenyl-Substituted Tetramic Acid Derivatives as Pest Control Agents and/or Herbicides | DDT, DDC, DAO | SMN1; SMN2 2872/4885KMT2A 1209/4885MEN1 3583/4885 |
| US-20070129252-A1 | 2-Halo-6-alkylphenyl-substituted spirocyclic tetramic acid derivatives | TBCA, CA6, TRIP13 | SMN1; SMN2 4187/4885KMT2A 2816/4885MEN1 4261/4885 |
| US-20230399337-A1 | NOVEL KINASE INHIBITORS EXHIBITING ANTI-CANCER ACTIVITY AND THEIR METHOD OF USE | ABL1, MCL1, ABL2 | SMN1; SMN2 4029/4885KMT2A 370/4885MEN1 2793/4885 |
| US-20240208902-A1 | CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS | MGLL, LPL, PNLIP | SMN1; SMN2 1934/4885KMT2A 2671/4885MEN1 3013/4885 |
| US-20070015771-A1 | Lonidamine analogs | LONP1, LPXN, QDPR | SMN1; SMN2 4352/4885KMT2A 3513/4885MEN1 454/4885 |
| US-20070043057-A1 | Lonidamine analogs | LONP1, LPXN, QDPR | SMN1; SMN2 4352/4885KMT2A 3513/4885MEN1 454/4885 |
| US-20070043045-A1 | Novel high affinity thiophene-based and furan-based kinase ligands | CDKL2, CDK2, CDKL1 | SMN1; SMN2 2211/4885KMT2A 806/4885MEN1 3348/4885 |
| US-20240018162-A1 | BIFUNCTIONAL DEGRADERS OF HEMATOPOIETIC PROGENITOR KINASE AND THERAPEUTIC USES THEREOF | TTK, HIPK1, CLK1 | SMN1; SMN2 2215/4885KMT2A 733/4885MEN1 3532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.