Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | UBE2N | P61088 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL433028 | 0.86 | P2RX7 (0.42) | MAPTKDM4EALDH1A1P2RX7ROCK2 | |
| SCHEMBL433833 | 0.85 | OPRM1 (0.47) | MAPTKDM4EALDH1A1OPRM1OPRK1 | |
| SCHEMBL435352 | 0.84 | P2RX7 (0.43) | SLC6A3MAPTKDM4EALDH1A1P2RX7 | |
| Hydrochloric Acid SCHEMBL433923 | 0.82 | HSD11B1 (0.49) | MAPTKDM4EALDH1A1P2RX7MEN1 | |
| SCHEMBL435241 | 0.82 | P2RX7 (0.42) | SLC6A3MAPTKDM4EALDH1A1P2RX7 | |
| SCHEMBL434266 | 0.82 | MAPT (0.53) | MAPTKDM4EALDH1A1OPRM1P2RX7 | |
| SCHEMBL435467 | 0.81 | ALDH1A1 (0.44) | MAPTKDM4EALDH1A1P2RX7MEN1 | |
| SCHEMBL434790 | 0.81 | OPRM1 (0.47) | KDM4EALDH1A1OPRM1P2RX7OPRK1 | |
| SCHEMBL433444 | 0.81 | SLC6A4 (0.47) | MAPTKDM4EALDH1A1OPRM1P2RX7 | |
| SCHEMBL432937 | 0.80 | LMNA (0.44) | MAPTKDM4EALDH1A1OPRM1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012410-A2 | KAPPA OPIOID RECEPTOR AGONISTS | DR. REDDY'S LABORATORIES LTD. (IN) | 2012-01-26 | — | — | WO | claimed |
| WO-2012012410-A2 | KAPPA OPIOID RECEPTOR AGONISTS | DR. REDDY'S LABORATORIES LTD. (IN) | 2012-01-26 | — | — | WO | disclosed |