Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.39 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL434790 | 0.91 | OPRM1 (0.47) | OPRM1OPRD1OPRK1CYP2D6ALDH1A1 | |
| SCHEMBL433030 | 0.85 | SLC6A3 (0.45) | OPRM1OPRK1ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL433028 | 0.84 | P2RX7 (0.42) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL433923 | 0.81 | HSD11B1 (0.49) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL433444 | 0.81 | SLC6A4 (0.47) | OPRM1OPRD1OPRK1ALDH1A1MEN1 | |
| SCHEMBL434266 | 0.80 | MAPT (0.53) | OPRM1OPRD1OPRK1CYP2D6ALDH1A1 | |
| SCHEMBL15380395 | 0.80 | OPRK1 (0.55) | OPRM1OPRD1OPRK1CYP2D6ALDH1A1 | |
| SCHEMBL433098 | 0.80 | OPRK1 (0.55) | OPRM1OPRD1OPRK1CYP2D6ALDH1A1 | |
| SCHEMBL435467 | 0.80 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ARAB9AKDM4E | |
| SCHEMBL435352 | 0.79 | P2RX7 (0.43) | ALDH1A1MEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012410-A2 | KAPPA OPIOID RECEPTOR AGONISTS | DR. REDDY'S LABORATORIES LTD. (IN) | 2012-01-26 | — | — | WO | disclosed |