Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | ME2 | P23368 | 2/20 | 0.33 |
| ▸ | ME1 | P48163 | 2/20 | 0.33 |
| ▸ | ME3 | Q16798 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4357646 | 0.91 | FKBP1A (0.43) | ME2ME1ME3GPR119ALDH1A1 | |
| SCHEMBL4351462 | 0.88 | HTR1A (0.40) | HRH3HTR1AKCNH2GPR119NPY2R | |
| SCHEMBL4350045 | 0.88 | MCHR1 (0.38) | KCNH2GPR119 | |
| SCHEMBL4355465 | 0.87 | HTR1A (0.35) | HRH3HTR1AKCNH2GPR119NPY2R | |
| SCHEMBL4361256 | 0.86 | OPRD1 (0.46) | — | |
| SCHEMBL4351631 | 0.84 | ALDH1A1 (0.40) | HRH3HTR1AKCNH2NPY2RALDH1A1 | |
| SCHEMBL4538463 | 0.83 | NPY2R (0.39) | HRH3HTR1AKCNH2GPR119NPY2R | |
| SCHEMBL13586016 | 0.83 | SMN1; SMN2 (0.43) | KCNH2GPR119ALDH1A1HPGD | |
| SCHEMBL13586042 | 0.82 | CYP3A4 (0.38) | HRH3HTR1AKCNH2ALDH1A1POLB | |
| SCHEMBL4362139 | 0.82 | MLNR (0.38) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |