Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 11/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4364150 | 0.88 | NAAA (0.35) | KCNH2GPR119 | |
| SCHEMBL4351462 | 0.86 | HTR1A (0.40) | KCNH2CYP2D6GPR119 | |
| SCHEMBL4357646 | 0.86 | FKBP1A (0.43) | MCHR1GPR119 | |
| SCHEMBL4355465 | 0.85 | HTR1A (0.35) | MCHR1KCNH2CYP2D6GPR119 | |
| SCHEMBL13586274 | 0.85 | CTSC (0.36) | MCHR1KCNH2HTR2CGPR119 | |
| SCHEMBL4351631 | 0.82 | ALDH1A1 (0.40) | MCHR1KCNH2 | |
| SCHEMBL4538463 | 0.81 | NPY2R (0.39) | MCHR1KCNH2CYP2D6GPR119 | |
| SCHEMBL4361256 | 0.81 | OPRD1 (0.46) | — | |
| SCHEMBL13586016 | 0.81 | SMN1; SMN2 (0.43) | MCHR1KCNH2GPR119 | |
| SCHEMBL13586042 | 0.80 | CYP3A4 (0.38) | MCHR1KCNH2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |