Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ME2 | P23368 | 1/20 | 0.36 |
| ▸ | ME1 | P48163 | 1/20 | 0.36 |
| ▸ | ME3 | Q16798 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13586016 | 0.92 | SMN1; SMN2 (0.43) | ALDH1A1KMT2AMEN1HPGDMCHR1 | |
| SCHEMBL4364150 | 0.91 | NAAA (0.35) | ALDH1A1HPGDME2ME1ME3 | |
| SCHEMBL4361256 | 0.89 | OPRD1 (0.46) | FKBP1AKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL4351462 | 0.86 | HTR1A (0.40) | ALDH1A1KMT2ATSHRMEN1LMNA | |
| SCHEMBL4350045 | 0.86 | MCHR1 (0.38) | MCHR1GPR119 | |
| SCHEMBL4355465 | 0.85 | HTR1A (0.35) | ALDH1A1TSHRKDM4EMCHR1LMNA | |
| SCHEMBL4351631 | 0.82 | ALDH1A1 (0.40) | ALDH1A1KMT2ATSHRMEN1MCHR1 | |
| SCHEMBL4538463 | 0.81 | NPY2R (0.39) | ALDH1A1TSHRMCHR1LMNAGPR119 | |
| SCHEMBL13586042 | 0.80 | CYP3A4 (0.38) | ALDH1A1TSHRMCHR1LMNAHTT | |
| SCHEMBL4360506 | 0.79 | GPR119 (0.47) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |