SCHEMBL435250

SCHEMBL435250

CN(C(=O)CF)c1cccc2ccccc12

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 12/20 0.59
TSHR P16473 3/20 0.40
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C19 P33261 1/20 0.40
NPSR1 Q6W5P4 2/20 0.39
MEN1 O00255 1/20 0.39
PER2 O15055 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
HTT P42858 1/20 0.39
KMT2A Q03164 1/20 0.39
CRY1 Q16526 1/20 0.39
CRY2 Q49AN0 1/20 0.39
LMNA P02545 1/20 0.39
MMP9 P14780 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13007694 0.85 SIGMAR1 (0.61) SIGMAR1TSHRALDH1A1KDM4ENPSR1
SCHEMBL29266069 0.84 SIGMAR1 (0.45) SIGMAR1TSHRALDH1A1KDM4ECYP1A2
SCHEMBL27431595 0.83 SIGMAR1 (0.59) SIGMAR1TSHRALDH1A1KDM4ECYP1A2
SCHEMBL24865037 0.80 SIGMAR1 (0.54) SIGMAR1TSHRALDH1A1KDM4EMEN1
SCHEMBL30804570 0.80 SIGMAR1 (0.54) SIGMAR1TSHRALDH1A1KDM4EMEN1
SCHEMBL29666490 0.79 SIGMAR1 (0.67) SIGMAR1
SCHEMBL1614544 0.79 SIGMAR1 (0.67) SIGMAR1
SCHEMBL3626830 0.79 SIGMAR1 (0.67) SIGMAR1TSHRALDH1A1KDM4EMAPT
SCHEMBL11570035 0.78 SIGMAR1 (0.56) SIGMAR1TSHRALDH1A1KDM4EHPGD
SCHEMBL8150820 0.77 SIGMAR1 (0.65) SIGMAR1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1666 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137082-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL SYNGENTA CROP PROTECTION AG (CH) 2026-05-21 US claimed
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
US-12471599-B2 Agricultural compositions comprising remodeled nitrogen fixing microbes PIVOT BIO, INC. (US) 2025-11-18 US claimed
EP-3578542-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-12 EP claimed
EP-3578543-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-08-20 EP claimed
US-20250185667-A1 AGRICULTURAL COMPOSITIONS COMPRISING REMODELED NITROGEN FIXING MICROBES HSBC BANK USA, N.A. 2025-06-12 US claimed
EP-3578541-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY, AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-05-28 EP claimed
US-20250017207-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2025-01-16 US claimed
EP-4422404-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2024-09-04 EP claimed
EP-4422402-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL Syngenta Crop Protection AG (CH) 2024-09-04 EP claimed
US-20150181877-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2015-07-02 US claimed
US-20130217745-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2013-08-22 US claimed
WO-2012069652-A2 FUNGICIDE MIXTURES SYNGENTA PARTICIPATIONS AG (CH) 2012-05-31 WO claimed
EP-2347655-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS Syngenta Participations AG. (CH) 2011-07-27 EP claimed
US-20110142802-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION, INC. (US) 2011-06-16 US claimed
EP-2332411-A1 Fungicidal compositions Syngenta Participations AG (CH) 2011-06-15 EP claimed
US-20100216640-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION, INC. (US) 2010-08-26 US claimed
US-20080076664-A1 Fungicidal Compositions SYNGENTA CROP PROTECTION, INC. 2008-03-27 US claimed
US-20080070785-A1 For controlling phytopathogenic diseases; synergistic SYNGENTA CROP PROTECTION, INC. (US) 2008-03-20 US claimed
US-20070244121-A1 Synergistic Fungicidal Compositions SYNGENTA CROP PROTECTION, INC. (US) 2007-10-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250017207-A1 FUNGICIDAL COMPOSITIONS CYP51A1, BROX, DPM1 SIGMAR1 3394/4885TSHR 4533/4885ALDH1A1 1605/4885
US-20110142802-A1 FUNGICIDAL COMPOSITIONS CYP4X1, CYP1B1, CYP4B1 SIGMAR1 3227/4885TSHR 2890/4885ALDH1A1 1313/4885
US-20260137082-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL NOTUM, CTRL, BROX SIGMAR1 2688/4885TSHR 3379/4885ALDH1A1 2077/4885
US-20100216640-A1 FUNGICIDAL COMPOSITIONS BROX, RER1, BLVRB SIGMAR1 1471/4885TSHR 2108/4885ALDH1A1 2619/4885
US-20150181877-A1 FUNGICIDAL COMPOSITIONS CYP51A1, ERG28, DPM1 SIGMAR1 4054/4885TSHR 4306/4885ALDH1A1 803/4885
US-20070244121-A1 Synergistic Fungicidal Compositions DDT, CRY1, HCN1 SIGMAR1 1578/4885TSHR 3282/4885ALDH1A1 2503/4885
US-20250185667-A1 AGRICULTURAL COMPOSITIONS COMPRISING REMODELED NITROGEN FIXING MICROBES MYB, NANS, NANP SIGMAR1 2119/4885TSHR 3824/4885ALDH1A1 3242/4885
US-12471599-B2 Agricultural compositions comprising remodeled nitrogen fixing microbes MYB, NANS, NANP SIGMAR1 2119/4885TSHR 3824/4885ALDH1A1 3242/4885
US-20080070785-A1 For controlling phytopathogenic diseases; synergistic BROX, EPM2A, MANBA SIGMAR1 3381/4885TSHR 4710/4885ALDH1A1 4291/4885
US-20130217745-A1 FUNGICIDAL COMPOSITIONS CBR3, C1S, C9 SIGMAR1 596/4885TSHR 1756/4885ALDH1A1 2348/4885
US-20080076664-A1 Fungicidal Compositions AKR7A2, CYP51A1, TUBA3C SIGMAR1 2471/4885TSHR 4021/4885ALDH1A1 1173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.