Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL434266 | 0.89 | MAPT (0.53) | P2RX7MAPTKDM4EALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL433923 | 0.88 | HSD11B1 (0.49) | P2RX7MAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL434779 | 0.88 | POLB (0.52) | P2RX7MAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL433860 | 0.86 | P2RX7 (0.55) | P2RX7LMNATP53 | |
| SCHEMBL433922 | 0.84 | SMN1; SMN2 (0.53) | P2RX7ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL435467 | 0.84 | ALDH1A1 (0.44) | P2RX7MAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL432970 | 0.84 | CYP1A2 (0.44) | P2RX7MAPTALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL433170 | 0.83 | SMN1; SMN2 (0.52) | P2RX7ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL434790 | 0.82 | OPRM1 (0.47) | P2RX7KDM4EALDH1A1RAB9APOLB | |
| SCHEMBL435241 | 0.79 | P2RX7 (0.42) | P2RX7MAPTKDM4EALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012410-A2 | KAPPA OPIOID RECEPTOR AGONISTS | DR. REDDY'S LABORATORIES LTD. (IN) | 2012-01-26 | — | — | WO | disclosed |