Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | FABP6 | P51161 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437195 | 0.91 | UHRF1 (0.35) | NOS3NOS1NOS2UHRF1HTT | |
| SCHEMBL442244 | 0.78 | ACHE (0.43) | ALDH1A1BACE1MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL437293 | 0.78 | ACHE (0.43) | NOS3NOS2ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL438598 | 0.77 | ACHE (0.41) | HTTKMT2A | |
| SCHEMBL441831 | 0.77 | ALDH1A1 (0.46) | NOS3NOS1NOS2ALDH1A1UHRF1 | |
| SCHEMBL21358444 | 0.77 | PDPK1 (0.47) | KDRMAPT | |
| SCHEMBL437503 | 0.75 | TNF (0.35) | ALDH1A1UHRF1 | |
| SCHEMBL437952 | 0.73 | ACHE (0.45) | BACE1HTTKMT2ACYP1A2 | |
| SCHEMBL438613 | 0.73 | BCHE (0.45) | ALDH1A1BACE1TSHRSMN1; SMN2FLT3 | |
| SCHEMBL437945 | 0.70 | ACHE (0.47) | NOS3NOS1NOS2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |