Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CD44 | P16070 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL441831 | 0.86 | ALDH1A1 (0.46) | TNFALDH1A1DHFRUHRF1ACHE | |
| SCHEMBL437195 | 0.84 | UHRF1 (0.35) | UHRF1 | |
| SCHEMBL436602 | 0.76 | ACHE (0.44) | ALDH1A1DHFRACHE | |
| SCHEMBL437126 | 0.75 | NOS3 (0.38) | ALDH1A1UHRF1 | |
| SCHEMBL438932 | 0.72 | ACHE (0.46) | TNFACHEPDPK1 | |
| SCHEMBL440082 | 0.72 | LMNA (0.47) | TNFALDH1A1ACHE | |
| SCHEMBL12786975 | 0.72 | TLR8 (0.39) | ALDH1A1 | |
| SCHEMBL442268 | 0.72 | ACHE (0.46) | TNFALDH1A1ACHEPDPK1 | |
| SCHEMBL30993822 | 0.72 | TLR8 (0.39) | ALDH1A1 | |
| SCHEMBL442137 | 0.72 | HTT (0.49) | TNFALDH1A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |