Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 2/20 | 0.30 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.30 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437126 | 0.91 | NOS3 (0.38) | UHRF1NOS3NOS1NOS2HTT | |
| SCHEMBL437503 | 0.84 | TNF (0.35) | UHRF1 | |
| SCHEMBL437293 | 0.76 | ACHE (0.43) | NOS3NOS2PSMB5 | |
| SCHEMBL442244 | 0.76 | ACHE (0.43) | HTTKMT2A | |
| SCHEMBL438598 | 0.76 | ACHE (0.41) | HTTKMT2AEGFR | |
| SCHEMBL21358444 | 0.75 | PDPK1 (0.47) | EGFRERBB2 | |
| SCHEMBL442328 | 0.73 | NR4A2 (0.47) | UHRF1NOS3NOS1NOS2KMT2A | |
| SCHEMBL438613 | 0.72 | BCHE (0.45) | HTT | |
| SCHEMBL437952 | 0.72 | ACHE (0.45) | HTTKMT2A | |
| SCHEMBL437945 | 0.69 | ACHE (0.47) | NOS3NOS1NOS2KMT2AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |